Three years after the first film, Stuart questions his ability after a grueling soccer match alongside George, who kicked him with a soccer ball. He becomes even more downhearted after George's model airplane gets broken in an accident because of him. However, Stuart's father, Frederick Little, tells him that for every Little, there is a "silver lining", a good thing that comes out of an apparently bad situation.
After singing the film's signature song "When You Wish Upon a Star", Jiminy Cricket explains that he is going to tell a story of a wish coming true. His story begins in the Tuscany workshop of a woodworker named Geppetto. Jiminy watches as Geppetto finishes work on a wooden marionette whom he names Pinocchio (a name his cat Figaro and fish Cleo both dislike). Before falling asleep, Geppetto makes a wish on a star that Pinocchio would be a real boy. During the night, a Blue Fairy visits the workshop and brings Pinocchio to life, although he still remains a puppet. She informs him that if he proves himself brave, truthful, and unselfish he will become a real boy and assigns Jiminy to be his conscience.
Jon Arbuckle (played by Breckin Meyer) plans to propose to his girlfriend Dr. Liz Wilson (played by Jennifer Love Hewitt), who is going on a business trip to London. Jon follows her to the United Kingdom as a surprise; After escaping from the kennel, Garfield (voiced by Bill Murray) and Odie sneak into Jon's luggage and join him on the trip. Garfield and Odie break out of the hotel room, then get lost.
John Brown is a humble, but clumsy security guard working at the Bradford robotics laboratory in Riverton, Ohio, run by Artemus Bradford and his daughter Brenda, whom Brown has a crush on. Brown wishes to become a police officer, with support from his niece Penny. Brenda and Artemus create a lifelike robotic foot as part of the Gadget Program, to create cybernetically augmented police officers. Tycoon Sanford Scolex attacks the lab, steals the foot, and has Artemus murdered before escaping in his limo. Brown goes chasing him down in his car, which leads to its being destroyed by Scolex's explosive cigar leaving brown for dead, but a bowling ball coming from the fiery blast of Brown’s destroyed car smashingly crushes Scolex's hand, forcing him to replace it with a mechanical claw.
Conrad and Sally Walden live in the city of Anville with their single mother Joan Walden, who works for neat-freak Hank Humberfloob. One day, just as Mr. Humberfloob calls in a new member of the "Humberfloob Family", the new worker, Jim McFinnigan shakes his hand in thanks (shocking everyone, as they are aware that one will be fired if whom shakes his hand without permission), which angers Mr. Humberfloob, screaming "FIRED!", and Jim runs out crying. He then puts on hand sanitizer and firmly warns Joan that she will be fired if her house is messy for the upcoming meet and greet party. At the house, Conrad trashes the house, causing their dog Nevins to run down the street in fright. Joan punishes Conrad for a week while re-cleaning the house. Their next door neighbor, Lawrence Quinn, whom Joan is dating to Conrad's dismay, brings back Nevins, and Sally is grateful. When Lawrence leaves, Joan is called back to the office again, leaving the kids with Mrs. Kwan, a lethargic babysitter, and making sure they are forbidden to enter the living room, which is being kept pristine for the upcoming party. Lawrence is constantly on the lookout for any mischief that Conrad is up to, as he wants nothing more than to send him away to military school for the rest of his life, earning Conrad the reputation of "troublemaker", while his sister is characterized as "perfect and well-behaved".
On the streets of Fifth Avenue, an orphaned kitten named Oliver is left abandoned after his fellow orphaned kittens are adopted by passersby. Wandering the streets by himself in search of someone to adopt him, Oliver meets a laid-back dog named Dodger who assists the kitten in stealing food from a hot dog vendor named Louie. Dodger then flees the scene without sharing his bounty with Oliver. Oliver follows Dodger all throughout the streets until he eventually arrives at the barge of his owner, a pickpocket named Fagin, along with his meal, to give to his friends: Tito the Chihuahua, Einstein the Great Dane, Rita the Saluki and Francis the Bulldog. Oliver sneaks into their home, located below the city's docks, and is discovered by the dogs. After a moment of confusion, Oliver is then received with a warm welcome. Fagin, owner of the dogs, comes in and explains that he is running out of time to repay the money he borrowed from Sykes, a ruthless shipyard agent and loan shark. Sykes tells Fagin the money must be paid in three days, or else. Sykes' Dobermans Roscoe and DeSoto attack Oliver but the cat is defended by Fagin's dogs. Immediately thereafter, a depressed Fagin returns to the barge, lamenting that he has only three days to find the money he owes Sykes. After the dogs cheer him up, Fagin is introduced to Oliver, and, considering that they all need help, accepts him into the gang.
Avec sa femme Rachel et leurs deux jeunes enfants Ellie et Gage, le docteur Louis Creed quitte Boston pour s'installer dans une région rurale du Maine. Au fond des bois près de sa nouvelle maison, Ellie découvre un vieux cimetière pour animaux de compagnie dans lequel des générations d'habitants de la région ont enterré leurs animaux de compagnie préférés. Peu après, une tragédie s’abat sur la famille : Church, le chat d'Ellie, meurt écrasé par un camion. Louis se tourne alors vers un étrange voisin, Jud Crandall. Celui-ci l'emmène au-delà du cimetière pour animaux, jusqu'à un cimetière indien. Il lui propose alors d'enterrer Church dans cette zone peu hospitalière. Sans le savoir, Jud et Louis viennent de déclencher une série d’événements tragiques avec de redoutables forces maléfiques. Pour sa part, Rachel est obnubilée par des visions de sa sœur, jadis morte dans de tristes circonstances, et dont le souvenir vient sans cesse la hanter.
At a satellite base in Northern Germany, a worker named Freidrich, who is delivering secret codes finds a Cocker Spaniel puppy outside his office. He takes the puppy inside and shows it to his Bloodhound Rex. Rex senses that something is wrong with the dog and barks at it, making the worker take him outside. Both get locked out of the office. Rex looks through the window and sees the puppy taking pictures of the secret codes and revealing itself to be an evil female hairless Sphynx cat named Kitty Galore in disguise. Rex turns out to be a dog agent and reports to HQ.
Ace Ventura is a private investigator living in Miami, Florida, who specializes in retrieval of tame or captive animals. Despite the success of his methods, he does not receive many assignments and therefore cannot pay rent or repair his battered 1970s Chevrolet Monte Carlo; furthermore, his eccentricities make him the laughing stock of the Miami-Dade Police Department.
Mrs. Carolyn Brody (Elizabeth Perkins) and her son Scott (Alexander Pollock) return home and the family's Bloodhound Buddy starts chasing a cat, a chase which ends with Buddy's capture by other cats in an ambush.
Alice (Kristine DeBell) offends her boyfriend William (Ron Nelson) by rejecting his advances. Upset, she falls asleep reading Alice in Wonderland. The white rabbit (Larry Gelman) appears to her in a dream and takes her into a sexual wonderland. The story loosely follows Carroll's original plot, and includes many of his characters, but with considerable sexual license.
In a New York City park, hippies have gathered with guitars to sing protest songs. Fritz and his buddies show up in an attempt to meet girls. When a trio of attractive females walk by, Fritz and his friends exhaust themselves trying to get their attention, but find that the girls are more interested in the crow standing a few feet away. The girls attempt to flirt with the crow, making unintentionally condescending remarks about blacks, while Fritz looks on in annoyance. Suddenly, the crow rebukes the girls with a snide remark and walks away. Fritz invites the girls to "seek the truth," bringing them up to his friend's apartment, where a wild party is taking place. Since the other rooms are crowded, Fritz drags the girls into the bathroom and the four of them have group sex in the bathtub. Meanwhile, the police (portrayed as pigs) arrive to raid the party. As the two officers walk up the stairs, one of the partygoers finds Fritz and the girls in the bath tub. Several others jump in, pushing Fritz to the side where he takes solace in marijuana. The two officers break into the apartment, but find that it is empty because everyone has moved into the bathroom. Fritz takes refuge in the toilet when one of the pigs enters the bathroom and begins to beat up the partygoers. As the pig becomes exhausted, a very stoned Fritz jumps out, grabs the pig's gun, and shoots the toilet, causing the water main to break and flooding everybody out of the apartment. The pigs chase Fritz down the street into a synagogue. Fritz manages to escape when the congregation gets up to celebrate the United States' decision to send more weapons into Israel.
Marmaduke (Owen Wilson) is a Great Dane living in rural Kansas with a cat named Carlos (George Lopez). His owner, Phil Winslow (Lee Pace), works for Bark Organic dog food. Phil is very strict, from Marmaduke's perspective.
In 2004 Nobita "Noby" Nobi is a fourth grader who constantly gets failing grades in his subjects due to his laziness and is always bullied by his classmates Suneo "Sneech" Honekawa and Takeshi "Big G" Goda. His great-great grandson from the 22nd century (year 2136), Sewashi, who watches him every day, travels to Nobita's timeline while bringing along his robotic cat Doraemon. Sewashi reveals that if Nobita keeps up his act, he will have a disastrous future: he will marry Gian's sister Jaiko, have his private company burned down, and will be left with a great debt. To circumvent this, he orders Doraemon to help Nobita, modifying Doraemon's nose to prevent him from returning to the future unless Nobita gains a better future.
Artist and graphics designer Patience Phillips (Halle Berry) is a meek people pleaser whose only support is her best friend Sally (Alex Borstein). She works for a cosmetics company called Hedare Beauty, which is ready to ship a new skin cream called Beau-Line, that is able to reverse the effects of aging. However, as Patience visits the factory where it is being manufactured, she overhears a discussion between the scientist, Dr. Ivan Slavicky (Peter Wingfield), and Laurel Hedare (Sharon Stone), the wife of company owner George Hedare (Lambert Wilson); speaking about the dangerous side effects from continued use of the product. Laurel's guards discover Patience and are ordered to dispose of her. Patience tries to escape using a conduit pipe, but the minions have it sealed and flush her out of it, drowning her. Lying washed up on the shore and lifeless, Patience is mysteriously brought back to life by an Egyptian Mau cat, who appeared at her apartment earlier, and from that moment on develops cat-like abilities.