Henry Hill says, "As far back as I can remember, I always wanted to be a gangster", referring to his idolizing the Lucchese crime family gangsters in his blue-collar, predominantly Italian-American neighborhood in East New York, Brooklyn. Wanting to be part of something significant, Henry quits school and goes to work for them. He is able to make a living for himself and learns the two most important lessons in life: "Never rat on your friends, and always keep your mouth shut", the advice given to him after being acquitted of criminal charges early in his career.
Zack Brown and Miri Linky are roommates in Monroeville, Pennsylvania (a Pittsburgh suburb). They have been friends since the first grade. Despite Miri working at the local shopping mall and Zack working at a coffee shop, they have not paid their utility bills in months, with Zack devoting much of his free time to a fanatic following of the Pittsburgh Penguins and his status in the community amateur hockey team, the Monroeville Zombies. After work, their water gets turned off before they go to their high school reunion.
After the death of his owner Mr. Wing (Keye Luke), the mogwai Gizmo (voiced by Howie Mandel) becomes the guinea pig of mad scientists working at Clamp Enterprises, an automatic state-of-the-art office building in Manhattan, run by eccentric billionaire Daniel Clamp (John Glover). At the mercy of the chief researcher Dr. Catheter (Christopher Lee), Gizmo is rescued by his friend Billy Peltzer (Zach Galligan) and his fiancee Katie (Phoebe Cates), both of whom work at Clamp Enterprises. Clamp quickly befriends Billy upon being impressed by his skills in concept design, also sparking the interest of Billy's superior Marla Bloodstone (Haviland Morris). Gizmo is left in the office, where water spills on his head and spawns new mogwai, including Mohawk (voiced by Frank Welker), who then has Gizmo locked in the vents. They eat after midnight, turning into gremlins.
Pee-wee Herman is a puer aeternus with a pimped-out bicycle that he treasures and that his neighbor, Francis Buxton, covets. A bike shop employee, Dottie, has a crush on Pee-wee, but he does not reciprocate it. Pee-wee's bike gets stolen while at the mall. He confronts Francis, who has an air-tight alibi. Pee-wee then offers a $10,000 reward for his bike. Francis, who did indeed pay to have someone steal the bike, is frightened by Pee-wee's relentlessness and then pays to have it sent away. After holding a meeting, Pee Wee angrily shouts Dottie down while she is giving suggestions to him and refused to admit he needed help from Dottie while telling her off. Now mad, Pee Wee gives Dottie a furious "I DON'T NEED ANYBODY!" Desperate, Pee-wee visits a psychic, Madam Ruby, who lies to him, claiming that the bike is in the basement of the Alamo. Pee-wee hitchhikes to Texas, getting rides from a fugitive, Mickey, and from a ghostly trucker, Large Marge.
In Madrid in 1980, Enrique Goded, a young film director, is looking for his next project when he receives the unexpected visit of an actor looking for work. The actor claims to be Enrique's boarding school friend and first love, Ignacio Rodriguez. Ignacio, who is using now the name Ángel Andrade, has brought with him a short story titled "The Visit" hoping that Enrique would be interested in making a film out of it giving him the starring role. Enrique is intrigued since "The Visit" described their time together at the Catholic school and it also includes a fictionalized account of their reunion many years later as adults.
Amy Mayfield (Jennifer Morrison) is unsure about her thesis. But after a conversation with security guard Reese Wilson (Loretta Devine), she decides to make a film about a serial killer murdering in the fashion of urban legends.
The comedian Alvy Singer (Woody Allen) is trying to understand why his relationship with Annie Hall (Diane Keaton) ended a year ago. Growing up in New York, he vexed his mother with impossible questions about the emptiness of existence, but he was precocious about his innocent sexual curiosity.
Planet Spaceball, led by the incompetent President Skroob, has wasted all of its air. Skroob schemes to steal air from the planet Druidia by kidnapping Princess Vespa, the daughter of King Roland on the day of her pre-arranged wedding to the narcoleptic Prince Valium. Skroob sends the villainous Dark Helmet to complete this task with Spaceball One, an impossibly huge ship helmed by Colonel Sandurz. Before they can arrive, Vespa herself abandons her marriage and flees the planet in her personal Mercedes spaceship along with her Droid of Honor, Dot Matrix.
Om Prakash Makhija (Shah Rukh Khan) is a junior artist in the 1970s Hindi film industry, in love with film star Shanti Priya (Deepika Padukone). One evening, Om views the premiere of Shanti's film Dream Girl, posing as Manoj Kumar. Later that night, Om becomes drunk and describes his vision of himself as a famous, wealthy film star winning the Filmfare Award for Best Actor to his friend Pappu (Shreyas Talpade) and some local children. At the shooting of a later film, Om rescues Shanti from a fire scene where of the fire has escaped control, and they become friends. One day, after following Shanti, he overhears her and producer Mukesh Mehra's (Arjun Rampal) conversation, that Mukesh and Shanti have married in secret and Shanti is pregnant and expects a traditional wedding. Mukesh pretends to be happy with the news, and invites Shanti at the set of their soon-to-be-made film Om Shanti Om. Mukesh promises to cancel the film, reveal their marriage to the public, and have a grand wedding on the set; but instead traps Shanti on the set and sets it on fire to prevent a financial loss and to protect his career. Shanti tearfully begs Mukesh to release her but he leaves anyway.
The film is set in Hollywood, Los Angeles. Mel Funn (Mel Brooks), a great film director, is now recovering from a drinking problem and down on his luck. He sets out to Big Picture Studios to pitch a new script to the Chief, aided by his ever-present sidekicks Dom Bell (Dom DeLuise) and Marty Eggs (Marty Feldman). His big idea: the first silent motion picture in forty years. At first the Chief (Sid Caesar), who is in danger of losing the studio to the (literally) rabid and greedy New York conglomerate Engulf & Devour (Harold Gould and Ron Carey), rejects the idea, but Funn convinces him that if he can get Hollywood's biggest stars to be in the film, he could save the studio.
On their way home from a family party, married couple David (Luke Wilson) and Amy Fox, (Kate Beckinsale) who are planning to divorce after their young son Charlie accidentally died, take a wrong turn on a remote mountain road. When their car breaks down, they discover they are lost in the middle of nowhere with no cell phone reception, and decide to start walking back to The Pinewood Motel where they had earlier consulted with a mechanic about noises with the car. The couple arrive at the motel where there are no other cars parked. At the counter desk, they couple hear piercing screams coming from the back room which makes Amy reluctant to stay. The motel manager, Mason (Frank Whaley) then appears and explains that the noises are coming from the television. The couple then book a room for the night.
Following his graduation from university in 1956, aspiring filmmaker Colin Clark (Eddie Redmayne) travels to London to get a job on Laurence Olivier's (Kenneth Branagh) next production. Hugh Perceval (Michael Kitchen) tells Colin that there are no jobs available, but he decides to wait for Olivier, whom he once met at a party. Olivier and his wife, Vivien Leigh (Julia Ormond), eventually show up and Vivien encourages Olivier to give Colin a job on his upcoming film The Prince and the Showgirl, starring Marilyn Monroe (Michelle Williams). Colin's first task is to find a suitable place for Marilyn and her husband, Arthur Miller (Dougray Scott), to stay at while they are in England. The press find out about the house, but Colin reveals he secured a second house just in case, impressing Olivier and Marilyn's publicist, Arthur P. Jacobs (Toby Jones).
Jim Hawkins is a young orphan who lives in the Admiral Benbow in England with his friends Gonzo and Rizzo. Jim listens to the tales of Billy Bones, who tells of his former captain, Captain Flint, who buried his treasure trove on a remote island and executed all of his crew so only he would own the island’s map. One night, one of Bones’ fellow crewmates Blind Pew arrives, giving Bones the black spot. Bones dies of a heart attack, but gives Jim the treasure map beforehand. An army of pirates attack the inn, destroying it, but the boys escape with the map.
In outer space, a United States-owned satellite blows up and one of the last remaining pieces, a beacon, is sent hurdling towards Earth where it lands in Australia, only to be swallowed by a crocodile. Back at the CIA, Agent Buckwhiler and Deputy Director Reynolds reveal that, in the wrong hands, the beacon can change the axis of power in the world, so they send two agents, Robert Wheeler and Vaughn Archer, down to Australia to retrieve the beacon. Department Director Ansell also secretly hires an operative of his own, Jo Buckley, to go and retrieve the beacon before Wheeler and Archer, so Ansell can take Reynolds' job.
Marty Faranan (Farrell) is a struggling writer in Los Angeles, California who dreams of finishing his screenplay, Seven Psychopaths. Marty's best friend, Billy Bickle (Rockwell), is an unemployed actor who makes a living by kidnapping dogs and collecting the owners' cash rewards for their safe return. His partner-in-crime is Hans Kieslowski (Walken), a religious man with a cancer-stricken wife, Myra. Billy helps Marty with Seven Psychopaths, suggesting he use the "Jack of Diamonds" killer, perpetrator of a recent double murder, as one of the seven "psychopaths" in his script. Marty writes a story for another psychopath, the "Quaker", who stalks his daughter's killer for decades, driving the killer to suicide and ultimately cutting his own throat to follow him to hell.