In the summer of 1963, Frances "Baby" Houseman (Jennifer Grey) is vacationing with her affluent Jewish American family at Kellerman's, a family friendly resort in the Catskill Mountains. The younger of two daughters, Baby is planning to attend Mount Holyoke College to study the economics of underdeveloped countries and then enter the Peace Corps. She was named after Frances Perkins, the first woman in the U.S. Cabinet. Her father, Jake (Jerry Orbach), is the personal physician and friend of Max Kellerman (Jack Weston), the resort's owner. Baby is befriended by Max's smart aleck grandson Neil (Lonny Price).
Peter Highman (Robert Downey, Jr.) is on a plane, flying home to be with his wife Sarah (Michelle Monaghan), who is due to give birth. Sitting behind Peter is a man named Ethan Tremblay (Zach Galifianakis), who is going to LA to be an actor and is planning to scatter his recently deceased father's ashes at the Grand Canyon. When Ethan misuses the words "terrorist" and "bomb" while talking to Peter, they are both escorted off the plane. This is only the first of a series of misadventures caused by the drastically dysfunctional Ethan. Peter, now on the No Fly List and missing his wallet, agrees to drive with Ethan to Los Angeles.
The film opens with narration from Kuzco, a teenage Inca emperor who has been transformed into a llama. He tells the story of how his life as a ruler used to be and how it was ruined "for no reason". However, in his flashback he is shown to have been rude and narcisissitic, albeit charismatic. He even goes so far as insulting the appearances of potential brides and throwing an old man out the window for "throwing off his groove." After Kuzko fires his conniving advisor, Yzma, for abusing her power, she comes up with a scheme to usurp the throne with the help of Kronk, her dim-witted but jovial henchman. Meanwhile, Kuzco meets with Pacha, a kind peasant and village leader, and tells him that he wants to demolish his hilltop family home to build himself a lavish summer home called "Kuzcotopia". Pacha protests, but is dismissed.
During Christmas 1955, an 11-year-old Hellboy is told a bedtime story by his adoptive father, Trevor Broom, involving an ancient war between man and magical creatures, started by man's greed. After defeat of the magical creatures' forces, the master of the goblin blacksmiths offers to build an indestructible mechanical army for the elven King Balor. Encouraged by his son Prince Nuada, Balor orders the building of this Golden Army. The humans are devastated by the army. Balor is ridden with guilt and forms a truce with the humans: Man will keep his cities and the magical creatures will keep their forests. Nuada does not agree with the truce and leaves in exile. The magical crown controlling the army is broken into three pieces, one going to the humans and the other two kept by the elves.
Child psychologist Samuel Faulkner (Hugh Grant) has an ideal romance with ballet teacher Rebecca Taylor (Julianne Moore). Rebecca is thinking about marriage and children. Samuel is against the idea of marriage as he is happy with how things are between them. This all changes when Rebecca declares she is pregnant and when questioned by Samuel about her birth control she replies birth control is only 97% time effective. His fears mount due to his encounters with overbearing couple Marty (Tom Arnold) & Gail (Joan Cusack) and their unruly daughters, as well as the confusing advice he gets from his perpetually single artist friend (Jeff Goldblum). They meet their Doctor Kosevich (Robin Williams) who happens to be Russian. Samuel is confused and unsure about what to do. Feeling neglected Rebecca leaves him and moves in with Marty and Gail. Samuel tries to contact her but she does not respond. When a girl makes a move on Samuel he declines saying he's not ready to move on yet. When he sees an ultrasound of his soon-to-be-born son, he decides that it is time to take responsibility before it is too late. He sells his Porsche buys a family van and gets back together with Rebecca. He marries her and they have the baby together.
Two years after the events in the previous film, the Baker family begins to undergo many changes, beginning with Lorraine (Hilary Duff) and her desire to study in New York. Their oldest daughter Nora (Piper Perabo) is now married to Bud McNulty (Jonathan Bennett) and heavily pregnant. They intend to move to Houston because of Bud's new job promotion.
Austrian Research geneticist Dr. Alex Hesse (Arnold Schwarzenegger) has a nightmare about infants urinating in a library. In the real world, he and his colleague Dr. Larry Arbogast (Danny DeVito), an obstetrician and gynecologist, have invented a fertility drug, "Expectane", that is supposed to reduce the chances of a woman's body rejecting an embryo and thus prevent a miscarriage. Unfortunately, they are not allowed to test it on women since the Food and Drug Administration has not yet approved the drug; so Hesse and Arbogast move forward in their research. In response, Hesse breaks into the laboratory and locks himself in. The head of the review board, Noah Banes (Frank Langella), informs Arbogast that while the FDA has denied their team the right of human experimentation, the team has managed to receive a donation from fellow geneticist Dr. Diana Reddin (Emma Thompson) from the ovum cryogenics department. When Hesse questions the chances of a woman taking an unapproved drug during pregnancy, Arbogast reveals that there is no need to identify the gender of the experiment and convinces Hesse to impregnate himself, using an ovum codenamed "Junior".
The film starts with a parody of the 1981 Indiana Jones action film Raiders of the Lost Ark. Afterwards, the babies are chased out of the temple by a boulder, which is revealed to be Didi Pickles who is at the baby shower at the Pickles' house, where Didi is pregnant with a second baby, which everyone believes will be a girl. Didi goes into labor and her friends rush her to the hospital. While this is happening, the kids crawl off. When the baby is finally born after a montage of past lives, it is a boy and they name him Dillon, after Didi's cousin. Dil quickly becomes a very spoiled baby, crying non-stop for attention, keeping all of the babies' toys for himself and refusing to share with Tommy. After a particularly nasty fight between Tommy and Dil over Tommy's teddy bear, Stu has a conversation with Tommy about being a big brother and the responsibility he now has and assures him that one day he will be happy to have Dil as his little brother. He also gives Tommy a locket with a picture of Tommy and Dil taped together and a watch inside which he calls his "sponsativity", his term for responsibility.
Homer Wells, an orphan, grows up in a Maine orphanage directed by kindly, avuncular Dr. Wilbur Larch. Homer is returned twice by foster parents; his first foster parents thought he was too quiet and the second parents beat him. Dr. Larch is addicted to ether and is also secretly an abortionist. Conditions at the orphanage are very spartan, but the children are treated with love and respect, and they are like an extended family. Each night before they go to sleep, Dr. Larch says, "Goodnight you princes of Maine, you kings of New England!" as both encouragement and a kind of blessing.
Claire Bartel is pregnant with her second child. At a routine checkup she is sexually molested by her new obstetrician, Dr. Victor Mott. Traumatized, she tells her husband, Michael, who encourages her to report him to the police. More women come forward with similar complaints, and multiple charges are prepared against Dr. Mott, who shoots himself. Later, Dr. Mott's pregnant widow is told by her lawyers that her husband's assets have been frozen because of the lawsuits and that she will lose her luxurious home. Mrs. Mott goes into early labor, loses her baby and, after hemorrhaging, is given an emergency hysterectomy. While recovering in the hospital, she sees a news story featuring Claire as the woman who alerted the police, leading Mrs. Mott to swear vengeance.
Following the fight at the end of Rocky, in which Apollo Creed has successfully defended his heavyweight title in a split decision, he and Rocky are taken to the same hospital. Apollo challenges Rocky to a rematch, but Rocky declines and announces his retirement. His girlfriend Adrian supports this choice, as do his doctors, who reveal he will require surgery for a detached retina, which could lead to permanent blindness. After Rocky is discharged from the hospital, he enjoys the benefits of his life's changes: Rocky's new fame attracts an agent who sees Rocky as a potential endorsement and sponsorship goldmine, and his sudden wealth encourages him to propose to Adrian. She happily accepts, and they marry in a small ceremony. Soon after, Rocky and Adrian happily learn that Adrian is pregnant.
Four years after the second film, Scott Calvin/Santa Claus (Tim Allen), and his wife, Carol (Elizabeth Mitchell), are expecting their first child as Christmas Eve approaches. Carol is missing her family, so Scott invites his in-laws, Sylvia and Bud Newman (Ann-Margret and Alan Arkin), up to the North Pole, along with his former wife, Laura (Wendy Crewson), her husband, Neil (Judge Reinhold), and their daughter, Lucy (Liliana Mumy), to keep Mrs. Claus company. Meanwhile, he is summoned to a meeting of the Council of Legendary Figures consisting of Mother Nature (Aisha Tyler), Father Time (Peter Boyle), the Easter Bunny (Jay Thomas), Cupid (Kevin Pollak), the Tooth Fairy (Art LaFleur), and the Sandman (Michael Dorn). Jack Frost (Martin Short) also arrives and is in trouble. He is jealous that he has no holiday or special occasion in his honor, and has been promoting himself during the Christmas season. Mother Nature accuses him of attempting to upstage Santa, and suggests sanctions against him. When Santa says that he is dealing with how to get the in-laws to come without revealing that he is Santa, Jack Frost manages to negotiate a light sentence of community service at the North Pole, helping Santa and the elves put up various Canadian-themed paraphernalia, as Carol's parents believe Scott is a toymaker in Canada. However, Frost's ultimate goal is to trick Santa into renouncing his position, with unknowing help from Curtis who accidentally blurts out what the Escape Clause is and where it is. Thus, Jack Frost sneaks into Santa's hall of snow globes (which contain images of all the Santas throughout world history) and steals a special one containing Santa Claus (aka Scott Calvin) that will invoke the Escape Clause, in which Santa must hold the Globe and say "I wish I'd never been Santa at all" thus sending him back in time and undoing his career as Santa. When Lucy discovers this crime Jack Frost freezes her parents and locks her in a closet. Jack Frost causes trouble for the family that makes Scott think that he must resign to make things better.
In a fairy tale, Princess Moanna, whose father is the king of the underworld, visits the human world, where the sunlight blinds her and erases her memory. She becomes mortal and succumbs to illness. The king believes that eventually, her spirit will return to the underworld.
Set in Atlanta, the film opens with fitness trainer Jules Baxter (Cameron Diaz) and her dance partner Evan Webber (Matthew Morrison) performing on the TV show Celebrity Dance Factor. They are crowned the winners of the show, but Jules vomits in their trophy, discovering that she is pregnant. Jules struggles when trying to balance her pregnancy with her normal active life. She has an ongoing argument with Evan over whether or not to have their son circumcised. During labor, she chooses not to have an epidural. She gives birth to a girl called Emerson, meaning their debate doesn't matter anymore. After giving birth, Jules and Evan get engaged.
Zoe (Jennifer Lopez) has given up on finding the man of her dreams and decided to become a single mother and undergoes artificial insemination. The same day she meets Stan (Alex O'Loughlin) when they both try to hail the same taxi. They run into each other twice more at a farmers market and a pet store. Stan convinces Zoe to go on a no-obligations date. Zoe is still uncertain whether she is pregnant or not and if she should tell Stan. The night she takes the test, Stan takes her for a romantic dinner in a garden. Things don't turn out as well as planned when he spills the wine and a fire occurs. At the end of the night Stan asks her to come to his farm during the weekend and Zoe finds out that she is pregnant.