Tom Brand est homme d’affaires, très pressé et ne pensant qu'à sa carrière. Il s'est même éloigné de sa femme Lara et de sa fille Rebecca. Pour l'anniversaire de sa fille, il décide de lui faire cadeau d'un chat, acquis auprès d'un étrange personnage. Après un violent accident, il tombe dans le coma et son esprit est à présent dans la tête de l'animal. Alors qu'il est confronté à ses erreurs passées et à une vie de quadrupède, il va essayer de se racheter auprès des personnes de son entourage.
The Creed family – Louis, Rachel, and their children Ellie and Gage – move from Chicago to Ludlow, Maine, where they befriend elderly neighbor Jud Crandall, who takes them to an isolated pet cemetery hidden behind the Creeds' new home.
Chance, a disobedient American Bulldog (voiced by Michael J. Fox) and narrator of the film, opens by explaining that he is the pet of Jamie Burnford (Kevin Chevalia), but expresses no interest in his owner or being part of a family. He shares his home with Shadow, an older and wiser Golden Retriever (voiced by Don Ameche) owned by Peter Burnford (Benj Thall), and Sassy, a smart-mouthed Himalayan cat (voiced by Sally Field), owned by their sister, Hope (Veronica Lauren). That morning, Bob Seaver (Robert Hays) marries Laura Burnford (Kim Greist), and Chance manages to cause chaos by digging into the wedding cake in front of all the guests.
On a golden spring day at the bank of a tranquil river, a young 12-year-old girl named Alice grows bored listening to her older 19-year-old sister read aloud from a history book of William I of England. When her sister chastises Alice's daydreaming, Alice tells her kitten Dinah that she can live in a nonsensical magical land called Wonderland. While daydreaming, Alice spots a waistcoat-wearing White Rabbit passing by, exclaiming that he is "late for an important date". Alice gives chase and follows him into a rabbit hole, and falls into a large furnished hole. Her dress catches her fall like a parachute and she floats gently down. She sees the White Rabbit disappear into a tiny door and tries to follow, but the door's talking knob advises her to alter her size using a mysterious bottle marked "Drink Me." The contents shrink her to a fraction of her normal size, but the door is locked and the key is out of reach. She then takes a bite of a cookie that says “Eat Me” and grows large enough to fill the entire room. She begins to weep large tears that flood the room. The doorknob then tells Alice to drink from the bottle again, which causes her to shrink once more. Alice falls into the bottle and passes through the door's keyhole and into Wonderland. She meets several strange characters including the Dodo and Tweedledee and Tweedledum who recount the tale of "The Walrus and the Carpenter".
College student Hana falls in love with a werewolf and has two half-werewolf children with him: a daughter, Yuki, and a year later a son, Ame. Soon after Ame's birth, their father is killed while hunting food for the children.
The story is of a girl named Haru, a quiet, shy and ditzy high school student who has a suppressed ability to talk with cats. One day, she saves a darkly-colored, odd-eyed cat from being hit by a truck on a busy road. The cat is Lune, Prince of the Cat Kingdom. As thanks, the cats give Haru gifts of catnip and mice, and she is offered the Prince's hand in marriage. Her mixed reply is taken as a yes.
During the times of the British Raj in India, Mowgli is the 5-year-old son of the widowed Nathoo, whose wife died in childbirth. Nathoo works as a tour guide. On one of his tours, he is leading Colonel Geoffrey Brydon and his men as well as Brydon's five-year-old daughter Katherine. That night, the deadly tiger Shere Khan attacks the encampment, killing some soldiers who had been hunting down several animals for fun in the jungle earlier, which had enraged him. When he tries to kill the third hunter, Buldeo, Nathoo defends Buldeo, who ungratefully leaves him to be mauled to death by Khan. In the confusion, Mowgli is lost in the jungle with his pet wolf, Grey Brother. Brydon and his men believe Mowgli has been killed too. Mowgli is taken by Bagheera, a gentle black panther, to the wolf pack. Mowgli also befriends a bear cub named Baloo.
Winnie the Pooh and his friends hear a strange noise and find a set of large, circular footprints in the Hundred Acre Wood. During the night, Tigger's house is damaged by what appears to be an earthquake. The friends believe that there is a heffalump in the woods. Rabbit organizes an expedition to go try to catch it. Roo wants to comes long, but the others tell him he is too young and small to go. Despite this, Roo slips out on his own in search of the heffalump. He finds one; a playful young creature named Heffridge Trumpler Brompet Heffalump IV - "Lumpy" for short. Roo is afraid of his captive at first, but the two quickly become friends and play.
In order to wipe out the Gaulish village by any means necessary, Caesar plans to absorb the villagers into Roman culture by having an estate built next to the village to start a new Roman colony.
Puppies from Washington become trapped in a truck heading to Ferntiuktuk, Alaska. Upon arrival, the Buddies meet Shasta, a young husky whose 11-year-old owner is determined to win the Alaskan sled dog race. The puppies decide to help Shasta pursue his dreams. Unfortunately, as Shasta has no parents, this puts the puppies in a predicament as there is nobody to teach them how to become snow dogs. Shasta manages to persuade a dog named Talon into teaching the puppies into becoming his new protégés.
Jill Young is seen as a child at the beginning of the film when she witnesses the death of her mother, Ruth Young (Linda Purl), and the mother of Joe, an infant mountain gorilla, at the hands of poachers led by Andrei Strasser (Rade Šerbedžija). Strasser loses both his right thumb and trigger finger to Joe, and swears revenge on the gorilla for the damage. Before she dies, Ruth tells Jill to take care of Joe, to which Jill agrees. Twelve years later, Jill has raised Joe who, because of a rare genetic anomaly, has now grown to a height of 16 1/2-feet (5 meters) and weighs 2,200 pounds (1,000 kilograms). As a result, the other gorillas won't accept him and both are now living in relative peace until a wildlife refuge director, Gregg O'Hara (Bill Paxton), convinces Jill that they would be safer from poachers if they relocate to the United States.
In Canada's Jasper National Park, Kate begins Alpha school with her father and grows up as a fully trained Alpha, but on her first hunt she crosses paths with two wolves from the Eastern pack who are lacking food in their own territory and nearly start a war. The two packs have had a bitter rivalry ever since Tony commanded the Eastern wolves to cross over into Western territory (against pack law) to get sufficient food. Winston and Tony meet up one night and arrange for Kate to marry Garth (Chris Carmack), Tony's son. Kate, having a sense of responsibility and duty, agrees for the good of the pack and meets Garth at the Howling Rock.
François Pignon, an unassuming divorced man with a teenage son who ignores him, lives a quiet and unremarkable life. When he learns he will be fired from his job as an accountant in a rubber factory, he contemplates suicide, but his new neighbor Jean-Pierre Belone, a former industrial psychologist, dissuades him from jumping from his balcony and suggests a way to keep his position. Belone proposes that Pignon start a rumor he is homosexual by inserting his image in sexually provocative snapshots of a gay couple in a bar and anonymously mailing them to his boss, Mr. Kopel. The factory's primary product is condoms, so the gay community's support is essential, and Kopel will have to keep Pignon on the payroll to avoid charges of anti-homosexual bigotry.
In 1962 in the Texas countryside, 14-year-old Walter Caldwell (Haley Joel Osment) is left by his irresponsible, dishonest mother, Mae (Kyra Sedgwick), to live for the summer with his reclusive, bachelor great-uncles, Hub (Robert Duvall) and Garth (Michael Caine) McCann, brothers said to have a secret fortune. Walter is given a room in the attic where he finds a photograph of a beautiful woman, who he later learns is Jasmine (Emmanuelle Vaugier), Hub's one true love. Soon after, relatives Ralph and Helen arrive with their children, hoping for a chance at the fortune. Thinking Walter is also after it, they threaten to take him to the Orphanage, making him run away. Walter makes his way to a gas station, and uses a phone booth to call the court reporting school which his mother told him she was attending only to learn she isn't there. The two uncles find him; Hub is glad to see him on his way, but Garth convinces Hub to bring him back home.
In the Australian Outback, a young boy named Cody rescues and befriends a rare golden eagle named Marahute, who shows him her nest and eggs. Later on, the boy unknowingly falls into an animal trap set by Percival C. McLeach, a local poacher wanted by the Australian Rangers. When McLeach finds one of the eagle's feathers on the boy's backpack, he is instantly overcome with excitement, for he knows that catching an eagle that size would make him rich because he had caught one before, which was Marahute's mate. McLeach throws Cody's backpack to a pack of crocodiles in order to trick the Rangers into thinking that Cody was dead, and kidnaps him in his attempt to force him to reveal the whereabouts of Marahute.