Kevin Wendell Crumb souffre d'un trouble dissociatif de l'identité. Il échange régulièrement avec sa psychiatre dévouée, le docteur Fletcher, qui a déjà pu distinguer vingt-trois personnalités différentes s'exprimer à tour de rôle durant leurs conversations. Selon Fletcher, Kevin aurait subi des maltraitances et des humiliations au cours de son histoire et une 24 e personnalité, plus sombre et plus menaçante que toutes les autres, nommée « la Bête », demeure encore enfouie. Le docteur Fletcher met en exergue le fait que son patient s'est forgé ces nombreuses personnalités différentes dans un besoin existentiel de se protéger des autres. La situation se complique lorsque Kevin enlève trois jeunes filles.
Clarice Starling (Jodie Foster) is pulled from her training at the FBI Academy at Quantico, Virginia by Jack Crawford (Scott Glenn) of the Bureau's Behavioral Science Unit. He assigns her to interview Hannibal Lecter, a former psychiatrist and incarcerated cannibalistic serial killer, whose insight might prove useful in the pursuit of a serial killer nicknamed "Buffalo Bill", who skins his female victims' corpses.
A low-level marijuana dealer named David Clark (Jason Sudeikis) who lives in Denver is robbed of his money and stash, some of which he owes to his wealthy drug lord supplier Brad Gurdlinger (Ed Helms). After David is brought to him, Gurdlinger forces David to smuggle marijuana from Mexico as a solution to clear his debt. Realizing that one man attempting to get through customs is too suspicious, he hires a middle-aged stripper neighbor stage-named Rose (Jennifer Aniston), a runaway and petty thief named Casey (Emma Roberts), and his 18-year-old neighbor Kenny (Will Poulter), to pose as a bogus family called the "Millers". When the Millers reach the compound, they find out that the amount of marijuana they were picking up is not "a smidge" as Gurdlinger had informed them, but actually two tons. Because of the extra load of the marijuana on the RV, one of the radiator hoses breaks while going up a steep incline. A family they had encountered at the border, the Fitzgeralds, consisting of Don (Nick Offerman), Edith (Kathryn Hahn), and Melissa (Molly Quinn), catch up to them and tow the Millers' RV to a repair shop. On the trip to the shop, David learns that Don Fitzgerald is a DEA agent after finding his badge and gun in the glove compartment.
High school sweethearts David (Woody Harrelson) and Diana Murphy (Demi Moore) are a married couple who travel to Las Vegas, hoping they can win enough money to finance David's fantasy real estate project. They place their money on red in roulette and lose.
The film begins shortly before Bridget's mother's (Gemma Jones) annual Turkey Curry Buffet. Bridget (Renée Zellweger) is ecstatic about her relationship with Mark Darcy (Colin Firth). However, Bridget's confidence in her relationship is shattered when she meets Mark's colleague, the beautiful Rebecca Gilles (Jacinda Barrett). Bridget meets her ex, Daniel Cleaver (Hugh Grant), at her job for Sit-Up Britain and is offered a position as the "Smooth Guidess". Bridget initially refuses, quoting that Daniel Cleaver is a "deceitful, sexist, disgusting specimen of humanity". Bridget is delighted to be asked by Mark to go to the "Law Council Dinner", assuming he will propose afterwards, but because balding Tories quietly take offense at her ad hominem claim that depriving the poor of welfare is something advocated by balding Tories, the night does not end well.
Kazakh television personality Borat Sagdiyev leaves Kazakhstan for the "Greatest Country in the World", the "U, S and A" to make a documentary at the behest of the Kazakh Ministry of Information. He leaves behind his wife Oxana and other inhabitants of his village – including his "43-year-old" mother, "No. 4 prostitute in all of Kazakhstan" sister, "the town rapist", and "the town mechanic and abortionist" – bringing along his producer Azamat Bagatov and a pet chicken.
The once-successful steel mills of Sheffield, South Yorkshire, have shut down and most of the employees have been laid off. Former steel workers Gary "Gaz" Schofield and Dave Horsefall have resorted to stealing scrap metal from the abandoned mills to sell. Gaz is facing trouble from his former wife, Mandy and her boyfriend Barry over child support payments that he's failed to make since losing his job. Gaz's son, Nathan, loves his father but wishes they could do more "normal stuff" in their time together.
The film starts with the same opening scene from The Conjuring, in which two young women and a young man are telling Ed and Lorraine Warren about their experiences with a doll called Annabelle which, they believe, is haunted.
The opening screen says: "Some of this actually happened."
In 1978, con artists Irving Rosenfeld (Christian Bale) and Sydney Prosser (Amy Adams) have started a relationship and are working together. Sydney has improved Rosenfeld's scams, posing as English aristocrat "Lady Edith Greensly". Irving loves Sydney, though is hesitant to leave his unstable and histrionic wife Rosalyn (Jennifer Lawrence), fearing he will lose contact with her son Danny, whom Irving has adopted. Rosalyn has also threatened to report Irving to the police if he leaves her.
The film follows the adventures of a group of friends through the eyes of Charles (Hugh Grant), a good-natured but socially awkward Briton, who is smitten with Carrie (Andie MacDowell), an American whom Charles repeatedly meets at four weddings and at a funeral.
Anthony "Tony" Manero (John Travolta) is a 19-year-old Italian American man from the Bay Ridge neighborhood of Brooklyn in New York City. Tony lives with his parents (Val Bisoglio and Julie Bovasso), and works at a dead-end job in a small hardware store. The stagnant monotony of his life is temporarily dispelled every Saturday night when Tony is "king of the dance floor" at 2001 Odyssey, a local disco club. Tony has four close friends: Joey (Joseph Cali); Double J (Paul Pape); Gus (Bruce Ornstein); and the diminutive Bobby C. (Barry Miller). A fringe member of this group of friends is Annette (Donna Pescow), a neighborhood girl who longs for a more permanent physical relationship with Tony.
After eight months of treatment for bipolar disorder, Pat Solitano is released from a mental health facility in Baltimore, and returns to Lansdowne, Pennsylvania into the care of his father Patrizio and mother Dolores. Pat soon learns that his estranged wife, Nikki, has moved away, and that his father is out of work and resorting to illegal bookmaking to earn money with the hopes of opening a restaurant. Pat is determined to get his life back on track and reconcile with Nikki, who obtained a restraining order against him after a violent episode sent him away.
Four high school seniors from western Michigan are good friends: Jim Levenstein (Jason Biggs), an awkward, nerdy and sexually naïve character whose dad Noah (Eugene Levy) attempts to offer sexual advice including purchasing and giving him pornography; Chris "Oz" Ostreicher (Chris Klein), a member of the high school lacrosse team; Kevin Myers (Thomas Ian Nicholas), their geeky leader who wants to lose his virginity with his girlfriend named Vicky (Tara Reid); and Paul Finch (Eddie Kaye Thomas), a mochaccino-drinking sophisticate and a nerd. They are four outsiders who are geeks, usually get laughed at by arrogant jock Steve Stifler (Seann William Scott). These four boys make a pact, at Kevin's prompting, to lose their virginity before their high school graduation after a dorky classmate, Chuck Sherman (Chris Owen), claims to have done so at a party hosted by Stifler an ignorant and obnoxious lacrosse player who happens to be a close friend of the group (to a lesser degree, Finch, with whom he has a love-hate friendship).
Thirteen years after graduating high school, Jim Levenstein (Jason Biggs), Chris "Oz" Ostreicher (Chris Klein), Kevin Myers (Thomas Ian Nicholas), Paul Finch (Eddie Kaye Thomas), and Steve Stifler (Seann William Scott) are well-established in their lives and careers. Jim is still married to Michelle (Alyson Hannigan) and now has a two-year-old son, Evan. Since the birth of their son, Jim and Michelle's sex life has deteriorated. Oz is an NFL sportscaster living in Los Angeles with his supermodel girlfriend Mia (Katrina Bowden). Kevin is married to Ellie and works from home as an architect. Finch tells his friends that he has been travelling the world, and still searching for his one true love. Stifler works as a temp at an investment firm, where he is also the victim of humiliating verbal abuse by his cold-hearted employer.
In 1951, two policemen, Nock and Staehl, investigate mathematician Alan Turing after an apparent break-in at his home. Turing's suspicious behaviour and lack of war records triggers Nock's suspicion that he might be a Soviet spy. During his interrogation by Nock, Turing tells of his time working at Bletchley Park.