Will Randall is bitten by a wolf while driving home in Vermont. Afterwards, he is demoted from editor-in-chief of a publishing house when it is taken over by tycoon Raymond Alden, who replaces him with Will's protégé Stewart Swinton. When Will thinks that his wife Charlotte is having an affair with Stewart, he rushes over to his house where Stewart sees Will angry and asks him what the problem is. Will bites Stewart and rushes upstairs to the room to find Charlotte half-naked. His worst fears are confirmed. Will becomes more aggressive, taking on the characteristics of a wolf.
At his son's wedding party, Edward Bloom (Albert Finney) tells the same tall tale he's told many times over the years: on the day Will (Billy Crudup) was born, he was out catching an enormous uncatchable fish, using his wedding ring as bait. Will is annoyed, explaining to his wife Joséphine (Marion Cotillard) that because his father lives in a fantasy world and has never told the straight truth about anything, he felt unable to trust him. He is troubled to think that he might have a similarly difficult relationship with his future children. Will's relationship with his father becomes so strained that they do not talk for three years. But when his father's health starts to fail from cancer, Will and the now pregnant Joséphine return to his hometown in Alabama to visit. On the plane, Will recalls his father's tale of how he braved a swamp as a child after he was dared by a few other children. He meets a witch (Helena Bonham Carter). She shows Don Price and another boy how they were going to die. They run away, frightened. When the witch shows Edward his death in her glass eye, he accepts it without fear. With this knowledge, Edward knew there were no odds he could not face.
In 1202, an army led by the three vampire elders (Markus, Viktor, and Amelia) arrives at a Lycan-ravaged village. Viktor and Amelia capture their target: Markus' brother, William Corvinus, the first and most powerful werewolf. Despite Markus' defiance, Viktor orders that William be imprisoned in a secret location forever.
Wilhelm Grimm (Matt Damon) and Jakob Grimm (Heath Ledger) arrive in French-occupied Germany during the early 1800s. They go to Karlstadt to rid the town of a witch's ghost. After killing the "ghost", it is revealed that the Brothers Grimm have actually set up a fake witch to trick the town. Afterwards, as they are celebrating, Italian torturer Mercurio Cavaldi (Peter Stormare) takes them to the French General Delatombe (Jonathan Pryce). Delatombe forces them to solve a mystery: The girls of the small village of Marbaden are disappearing, and the villagers are convinced that supernatural beings are responsible. The Grimms are charged with finding who is responsible, and they soon discover that it is the work of a real supernatural force: a beautiful, yet evil, 500-year-old Thuringian Queen (Monica Bellucci) stealing young girls to restore her own beauty. Will and Jake have a complicated relationship; Jake is the smaller, younger, more sensitive one that Will feels he needs to protect. Will is often very hard on Jake (dating all the way back to their childhood, when Jake spent their money that was to be used for medicine for their dying sister on "magic beans") and orders him around. Will is somewhat of a womanizer and wants to make money, whereas Jake is more interested in fairy tales and adventures. Jake feels that Will doesn't care about or believe in him; but Will is just frustrated about the way Jake acts so spontaneously, making it hard for Will to protect him.
For generations, a secret war has been waged between vampires and Lycans, an ancient species of werewolf. Selene, a Death Dealer, a vampire specialized in assassinating Lycans, tracks two Lycans. Selene's motivation goes beyond duty; she also wants revenge because, 600 years ago when she was a child, Lycans slaughtered her family. The vampires believe they defeated the werewolves many centuries ago and killed their leader, Lucian, and that they must kill the surviving Lycans. Selene locates the Lycans' den and learns they have developed a new kind of bullet capable of killing the vampires.
New York City teenager Clary Fray begins seeing a strange symbol, worrying her mother Jocelyn Fray and her mother's friend Luke Garroway. Later, at a nightclub with her friend, Simon Lewis, Clary is the only person who sees Jace Wayland killing a man. Meanwhile, Jocelyn is abducted by two men, Emil Pangborn and Samuel Blackwell, but she is able to call Clary and warn her about someone named Valentine. Jocelyn drinks a potion putting her in a comatose state. Returning home, Clary finds her mother missing and is then attacked by a demon. Jace appears and kills it. Jace explains that he and her mother Jocelyn are both Shadowhunters (also called Nephilim), warriors that slay demons and rule over the downworlders. Clary has inherited her powers, including the ability to use runes.
Quelques jours avant Halloween, Sonny et Sam acceptent d'aller nettoyer une maison abandonnée dans leurs petite ville, Wardenclyffe, dans l'état de New York. Mais les deux garçons ignorent que cette demeure était celle du célèbre R. L. Stine, connu pour sa série de livres d'horreur Chair de poule, avant que ce dernier parte s'installer anonymement dans un autre état avec sa fille.
The film tells the story of Lucian, the first werewolf born in human form and the first to be called a Lycan. Viktor, a vampire elder, raises the child, and envisions a race of Lycan slaves that could keep guard of the coven's fortress during the day and be used as laborers by the vampires at night. To this end, Viktor demands from the local human nobles a tribute of silver, with which to keep his slaves under control. As Lucian grows up, he and Viktor's daughter Sonja (Rhona Mitra) fall in love and begin a secretive intimate relationship in their adult years. Sonja is reckless and insubordinate, and one night Lucian escapes and rescues Sonja from his werewolf brethren. Viktor, despite acknowledging that Lucian saved his daughter, cannot forgive the escape and locks Lucian away.
Valerie is a young woman who lives in the village of Daggerhorn, on the edge of a forest plagued by a werewolf, with her parents, Cesaire and Suzette, and older sister Lucie. She is in love with the town woodcutter Peter, but her parents have arranged for her to marry Henry Lazar, son of the wealthy blacksmith Adrien Lazar. Valerie and Peter plan to run away together, only to learn that the Wolf has broken its truce not to prey on the townspeople in exchange for cattle stock sacrifices and has murdered Lucie, who is revealed to have had a crush on Henry Lazar.
Après s'être éloigné de sa fille Ève pour éviter de la mettre en danger, Selene continue sa fuite et sa recherche de son compagnon, Michael Corvin. Elle refuse malgré tout l'aide de David, l'un de ses alliés. Mais quand elle est contactée par les membres du Conseil des Vampires qui acceptent de pardonner ses actions en échange de son aide, Selene est obligée de retourner parmi les siens pour entraîner des vampires à se battre contre les lycans qui préparent en secret une nouvelle attaque avec leur nouveau chef, Marius.
Becca Crane (Jenn Proske) moves to Sporks to live with her clueless father, Sheriff Frank (Diedrich Bader), after her mother starts an affair with Tiger Woods. Meanwhile, killings have been happening to random people and the number one suspects are the Canadians. It is in fact a group of vampires, who are (apparently) commonly confused with the Black Eyed Peas. Becca is quickly befriended by many students at her new high school, (which is odd, considering the welcome she was given) including Jennifer (Anneliese van der Pol) but she is intrigued by the mysterious and aloof Edward Sullen (Matt Lanter), who perplexes her during their time in the biology class, despite thinking she smells of tuna.
Seventeen-year-old high school student Scott Howard (Michael J. Fox) is sick of being average and wishes he were special. His father, Harold (James Hampton), runs a local hardware store. Scott plays basketball for his high school's team, the Beavers, with a not-so-good win-loss record. The girl of his dreams, Pamela Wells (Lorie Griffin), is dating Mick McAllister (Mark Arnold), a jerk from an opposing high school team, the Dragons. After another of the team's losses, Scott begins to notice strange changes to his body. While at a party, Scott keeps undergoing changes and eventually he returns home, locks himself in the bathroom, and undergoes a complete change and becomes a werewolf, while his father demands that he open the door. He tries to refuse, only to finally give in and find his father has also transformed. Harold never told his son about the condition because "sometimes it skips a generation" and he was hoping it would not happen to Scott. Needing someone else to share his secret, Scott confides his best friend, Stiles Stilinski (Jerry Levine), who accepts Scott's werewolf status. However, Scott inadvertently reveals his transformation to the public at one of his basketball games. After shortly stunning the crowd with The Wolf, Scott goes on to amaze them with his newfound basketball skills.
In 1795, Dr. Victor Frankenstein (Aden Young) creates a monster (Aaron Eckhart), a soulless creature patched together from corpses, and then rejects it, disgusted with what he's made. In a fit of rage, the creature kills Victor's wife Elizabeth (Virginie Le Brun) and Victor chases it to the Arctic to get revenge, but succumbs to the weather. The creature buries his creator in the Frankenstein family crypt and is then attacked by demons before being rescued by the gargoyles Ophir (Mahesh Jadu) and Keziah (Caitlin Stasey), who bring it before the gargoyle queen Leonore (Miranda Otto) and their commander Gideon (Jai Courtney). Leonore explains that they were created by the Archangel Michael to battle demons on Earth and protect humanity. They name the creature "Adam" and invite him to join them, but he declines and departs after being given heavy, baton-like weapons to protect him, as more demons will come after him. The weapons allow him to "descend" demons (destroying their bodies and trapping their souls in Hell) as they have the symbol of the Gargoyle Order carved on them.
In the underground Facility, senior technicians Gary Sitterson and Steve Hadley discuss plans for a mysterious ritual. A similar operation undertaken by their counterparts in Stockholm has just ended in failure.
College student Hana falls in love with a werewolf and has two half-werewolf children with him: a daughter, Yuki, and a year later a son, Ame. Soon after Ame's birth, their father is killed while hunting food for the children.