In 391 AD, Alexandria is part of the Roman Empire, and Greek philosopher Hypatia (Rachel Weisz) is a teacher at the Platonic school, where future leaders are educated. Hypatia is the daughter of Theon (Michael Lonsdale), the director of the Musaeum of Alexandria. Hypatia, her father's slave, Davus (Max Minghella), and two of her pupils, Orestes (Oscar Isaac) and Synesius (Rupert Evans), are immersed in the changing political and social landscape. She rejects Orestes's love (she offers him her bloody menstrual towel, to show him that love has its drawbacks, while studying has none): she prefers to devote herself to science. Davus assists Hypatia in her classes and is interested in science, and is also secretly in love with her.
Salvador Mallo est un réalisateur qui a connu le succès mais qui ne réalise plus de films à cause de nombreuses douleurs physiques dont il souffre. Par hasard, il retrouve Alberto Crespo, un acteur avec qui il s'est fâché trente ans auparavant. Il se remémore son enfance avec sa mère à Paterna.
Plastic surgeon Robert Ledgard was successful in cultivating an artificial skin resistant to burns and insect bites, which he calls "GAL", that he says he has been testing on athymic mice. He presents his results in a medical symposium but when he privately discloses he has also conducted illegal transgenic experiments on humans, he is forbidden to continue with his research.
Ángela Vidal (Manuela Velasco), and her cameraman, Pablo, are covering the night shift in one of Barcelona's local fire stations for the documentary television series While You're Sleeping. While they are recording, the firehouse receives a call about an old woman, Mrs. Izquierdo, who is trapped in her apartment and screaming. Ángela and Pablo accompany two of the firefighters, Álex and Manu, to the apartment building, where two police officers are waiting. As they approach the old woman, she becomes aggressive and attacks one of the officers, biting his neck.
"Harry Caine" is a blind writer who shares his life with his agent Judit and her adult son, Diego. Slowly, events in the present begin to bring back memories of the past. Harry hears that millionaire Ernesto Martel has died; a young filmmaker, Ray X, appears and turns out to be Martel's son, Ernesto, Jr. After Diego is hospitalized for an accidental drug overdose in a Madrid nightclub, Harry collects Diego from the hospital and looks after him to avoid worrying his traveling mother. The main storyline is told in flashback as Harry reluctantly tells Diego a tragic tale of fate, jealousy, abuse of power, betrayal, and guilt.
Le jeune homme d'affaires Adrián Doria se réveille à l’hôtel à côté du cadavre de sa maîtresse, Laura. Accusé d'assassinat, il va passer en procès. Afin d'éviter un conflit d'intérêt, son ami avocat, Felix Leiva, lui trouve une avocate qui le coache pour son procès. Le temps presse car l'accusation a appelé un invité surprise dont l'identité est tenue secrète à témoigner contre Adrián...
Hache Mario Casas flies back to Barcelona after spending two years in London, away from friends and family, and trying to forget his first love and Pollo's Alvaro Cervantes death, his best friend. His brother picks him up from the airport and lets him stay with him. After he settles himself in, he sees his bike covered with a sheet. While looking at it, he reminisces on the past. Hache takes his bike for a spin and lands in the port where he used to race illegally. As soon as he gets there he receives a call, turns out Katina Marina Salas found out through Alex (Hache's brother) that he just got back; they both agree to meet at a park. When he arrives at the park, Hache sees Chino Lucho Fernandez who tells him that things have changed. Chino invites him to a get-together in a restaurant with their other friends, Hache tells him he'll go in a while. While waiting sitting on a bench, Katina surprises him and they both sit down for some catch up. Katina asks Hache if he has missed Babi and tells him that she's seen her, but that she has changed. Hache invites her to the get-together, but Katina declines the invitation and they part ways promising to keep in touch. Hache gets on his motorcycle and is seen been followed by Gin Clara Lago a photographer.
The story takes place during the 17th century in the Spanish Empire. Diego Alatriste is a soldier in the service of King Philip IV of Spain, during the Eighty Years War. The story begins in the Netherlands, where the tercio of Diego Alatriste fights against the Dutch during the Dutch Revolt. Lope Balboa (father of Íñigo and friend of the captain) is killed here. Diego decides to return to Madrid where he receives the young Íñigo Balboa in his care.
Tadeo Jones (voiced in English by Kerry Shale) is a bricklayer from Spain who lives in Chicago, working on the construction of the city's subway. Ever since he was five years, he has dreamed of being a professional archaeologist. After being fired from his job as a bricklayer for daydreaming and for his dog urinating on the construction foreman, Tad visits his friend Professor Humbert (voiced by Mac McDonald), asking for the professor's help in investigating an apparently vintage bottle of Coca-Cola Tad found on the construction site. The professor receives a letter from his friend Professor Lavrof summoning him to Peru to re-unite his half of a stone "key" that will unlock the legendary Incan city of Paititi. Arriving at the airport, Professor Humbert suffers an accident after taking the wrong pills and is taken to the hospital. Meanwhile, a member of the nefarious firm Odysseus Inc. is spying on them and sends the photo to the other members who are in the Sechura Desert.
À la veille de quitter Madrid pour s'installer au Portugal avec son amant Lorenzo, Julieta rencontre fortuitement Beatriz, amie d'enfance de sa fille Antía. Elle apprend ainsi que cette fille qui est partie sans donner de nouvelles il y a plus de douze ans vit encore, en Suisse, avec trois enfants.
L'eurodéputé italienne Giannina Ricci (célèbre pour sa lutte contre les entreprises polluantes) vient en Espagne pour dénoncer publiquement une multinationale espagnole. La direction de l'entreprise s'inquiète et suborne quelques hauts responsables de la police pour que la protection de l'eurodéputé ne soit pas la meilleure possible. C'est ainsi que Jose Luis Torrente, récemment réincorporé dans la police, a la tâche de protéger l'italienne.
Marco Montes est l'entraîneur adjoint de l'équipe de basket de l'Estudiantes Madrid en Liga ACB. Personnage arrogant et de mauvaises manières, il finit par être licencié de son travail après une altercation en plein match avec l'entraineur principal de l'équipe. Parallèlement, son couple bat de l'aile car Sonia, sa compagne, désire un enfant, mais lui tergiverse et fuit cette responsabilité. Un soir, il s'enivre de dépit dans un bar et prend le volant. Il est alors responsable d'un accident de la route. Arrêté en état d'ivresse avancée, il se voit puni d'une lourde amende. Il doit alors choisir entre deux années de prison ou 90 jours de travail d'intérêt général au sein d'une équipe de basket appelée "Les Amis" et constituée de sportifs débutants handicapés. Après un premier rejet de l'idée, il finit par s'y plier à contrecœur, jusqu'à découvrir qu'il peut beaucoup apprendre du monde du handicap. Peu à peu, l'équipe devient de plus en plus compétitive et se qualifie pour le championnat national.