A year after the events of Extinction, the Alice clones (Milla Jovovich) attempt to kill Albert Wesker (Shawn Roberts) at the current Umbrella Headquarters, Tokyo. The clones manage to kill the entire branch, but Wesker makes his way to his private charter tiltrotor plane and escapes before activating a bomb, leaving a massive sinkhole. However, the real Alice boarded his aircraft beforehand. As she pulls a gun on him, Wesker injects her with Anti-Virus before the lack of a pilot makes the aircraft crash in the mountains outside Tokyo. Only Alice emerges from the crash alive.
The story begins five days after the assault on the Abnegation faction by Erudite leader Jeanine's mind-controlled Dauntless soldiers. Dauntless leader Eric and his platoon search through the wreckage of Abnegation for a box of unknown origin that contains the symbols for each faction. They recover the box and take it to Erudite. Jeanine claims it contains data from the city's founders and the means to end the Divergence problem–the issue of individuals having the qualities of multiple factions. Only a Divergent can open the box, so she orders all Divergents hunted down and captured.
Dix ans après la fermeture de la brèche, le monde se reconstruit et vit désormais en paix sans les Kaijûs. Jake, fils du célèbre Marshall Stacker Pentecost (mort en héros), vit de vols et de troc tout en fuyant le passé familial. Il va faire la connaissance de la jeune Amara Namani, qui a fabriqué son propre Jaeger (les robots géants qui ont permis d'affronter les monstres). Ils sont tous deux arrêtés pour vol de matériel de Jaeger et construction illégale de Jaeger, et afin d'éviter la prison, sont obligés d'accepter d'être embarqués sur une base militaire en Chine où Jake retrouve son ancien copilote de jaeger, Nate Lambert, afin de former les nouvelles recrues pilotes, qu'Amara rejoint. Sur place, tout le monde est en effervescence car les Jaegers sont sur le point d'être rendus obsolètes par le vote d'un programme de drones produits par Shao Corporation et développés par Liwen Shao et le Dr Newton Geiszler. Jake retrouve par ailleurs sa demi-sœur, Mako Mori, devenue Secrétaire Générale du Pan Pacific Defense Corps. Mais alors que le sommet pour le vote est sur le point de commencer à Sydney (QG du PPDC), un Jaeger illégal débarque et attaque la ville, tuant Mako Mori.
In a futuristic dystopian Chicago, the society is divided into five factions: Abnegation (the selfless), Amity (the peaceful), Candor (the honest), Dauntless (the brave), and Erudite (the intellectual). The remaining population are the Factionless, who have no status or privilege in this society. When children reach the age of 16, they undergo a serum-induced psychological test which indicates their best-suited faction, then are allowed to choose any faction as their permanent group at the subsequent Choosing Ceremony.
In 2077, the Earth has been devastated by war with an extraterrestrial invader, the Scavengers (Scavs). Humanity is relocating to Saturn's moon Titan via the Tet, a large tetrahedron-shaped space station. Gigantic offshore fusion energy generators drain the oceans to produce power for the colonists on Titan.
In the beginning of the 21st century, the polar ice caps melted and the sea level rose to cover every continent on Earth. Surviving humans were scattered across the ocean on ramshackle floating communities known as atolls, mostly built from scrap metal and decrepit sea vessels. Over time, the survivors eventually forget that they ever lived on firm ground, adapting a mythological place named "Dryland" somewhere in the ocean.
In the summer of 1982, Sam Brenner and Will Cooper are thirteen-year-olds who love playing in the local arcade. Brenner enters an arcade game world championships. At the event, the MC tells that a time capsule will be launched into space containing a videocassette that includes scenes from the championships. Brenner and Cooper meet Ludlow Lamonsoff, a child who's in love with Lady Lisa, the main character of the game Dojo Quest. Brenner succeeds in every game, but finally loses to Eddie Plant in Donkey Kong.
Flint Lockwood is a wannabe-scientist who lives in Swallow Falls, a tiny island in the middle of the Atlantic Ocean that has sardines as the base of its economy. Flint lives with Tim, his widowed technophobic father who misunderstands his son's talent, and his pet monkey, Steve. Despite Flint's zealous enthusiasm, his inventions, including spray-on shoes, a remote controlled television, rat birds, hair-un-balder, and a flying car, all ended in failure.
Alice (Milla Jovovich) and the others on the Umbrella Corporation freighter Arcadia face an attack by a fleet of tiltrotors led by Alice's former ally, Jill Valentine (Sienna Guillory), who is being mind controlled by Umbrella through a scarab device attached to her chest. Alice causes a tiltrotor to crash into Arcadia, resulting in an explosion that knocks her out and into the water. The fates of Chris Redfield, Claire Redfield and K-Mart are ambiguous.
Dans les années 1920, les parents de Katherine Coleman apprennent que leur fille possède un don pour les sciences, qu'elle doit parfaire en fréquentant une école pour Noirs (les Blancs étant dans des écoles séparées) car elle est dotée d'aptitudes intellectuelles supérieures. En 1962, devenue mathématicienne, Katherine Coleman (désormais Goble) travaille au sein d'un groupe de calculatrices humaines, sur le campus ouest du Centre de recherche Langley à Hampton, en Virginie, aux États-Unis, avec deux amies et collègues : l'aspirante ingénieure Mary Jackson et la superviseure d'équipe Dorothy Vaughan. À la suite du lancement réussi de Spoutnik 1, Al Harrison, directeur du Space Task Group, exige encore plus d'efforts de la part des employés sous sa supervision, de crainte que les Soviétiques ne mettent en orbite une bombe H pouvant exploser au-dessus du sol américain. Goble est envoyée dans son groupe pour vérifier les calculs, devenant la première Afro-Américaine à participer à ce groupe de recherche. Au début, elle est ignorée de ses collègues blancs et doit travailler à partir de données partiellement masquées (Goble n'ayant pas le niveau d'habilitation nécessaire) sous les ordres de Paul Stafford, un homme croyant en sa supériorité intellectuelle et refusant de reconnaître le travail de Katherine.
In the late 21st century, global warming has flooded coastlines, drastically reducing the human population. There is a new class of robots called Mecha, advanced humanoids capable of emulating thoughts and emotions. David (Haley Joel Osment), a prototype model created by Cybertronics of New Jersey, is designed to resemble a human child and to display love for its human owners. They test their creation with one of their employees, Henry Swinton (Sam Robards), and his wife Monica (Frances O'Connor). The Swintons' son, Martin (Jake Thomas), was placed in suspended animation until a cure can be found for his rare disease which is caused by the Sinclair virus. Initially frightened of David, Monica eventually warms enough to him to activate his imprinting protocol, which irreversibly causes David to have an enduring childlike love for her. He is also befriended by Teddy (Jack Angel), a robotic teddy bear, who takes it upon himself to care for David's well-being.
In 1928, a solitary mountaineer encounters a glowing sphere. He loses consciousness and when he wakes, the sphere has gone and there is a scar on his hand where a sample of his DNA has been taken.
God and Lucifer are engaged in a war for the souls of humanity; a standing wager for the souls of all mankind. Angels and demons are forbidden to manifest on Earth, but they are allowed to possess and influence humans, and half-breeds are used to peddle influence. Exorcist John Constantine was born with the power to see angels and demons. At age 15, he committed suicide to escape his visions, but he was revived after spending two minutes in Hell, and his soul is bound for Hell when he dies for the sin of taking his own life.