At the beginning of the film, we learn that the story takes place in one of many alternate worlds, in which a person's soul is contained within an animal companion called a dæmon (pronounced demon). The Magisterium, represented as a unified religious power, exercises power in the secular world. Lyra Belacqua, an orphan that resides in Jordan College, in a city that resembles Oxford, with her dæmon Pantalaimon (Pan), accidentally witnesses a Magisterium member poison her uncle's bottle of Tokay. Lyra then warns her uncle, Lord Asriel, who instructs her to remain in hiding. Lyra watches Asriel give a presentation regarding Dust, a particle that the Magisterium has forbidden the mention of. The college gives Asriel a grant to fund a northern expedition.
Duke (Channing Tatum) has become the leader of the G.I. Joe unit, which is framed for stealing nuclear warheads from Pakistan by Zartan (Arnold Vosloo), who is impersonating the President of the United States (Jonathan Pryce). The unit is subsequently decimated in a military air strike with Duke among the casualties. The only survivors are Roadblock (Dwayne Johnson), Flint (D.J. Cotrona), and Lady Jaye (Adrianne Palicki).
In 2003, Dr. Serena Kogan (Helena Bonham Carter) of Cyberdyne Systems convinces death row inmate Marcus Wright (Sam Worthington) to sign over his body for medical research following his execution. One year later, the automated Skynet system is activated, begins to perceive humans as a threat, and eradicates much of humanity with nuclear weapons in the event known as "Judgment Day".
A race of extraterrestrials called Mimics has taken over continental Europe. In England, General Brigham, head of humanity's United Defense Force, orders Major William Cage, a public affairs officer with no combat experience, to cover the next day's amphibious assault in France. Cage objects to the dangerous assignment and threatens to blackmail Brigham to avoid it. Brigham has Cage arrested; Cage is knocked out trying to escape. He wakes in handcuffs at a forward operating base at Heathrow Airport and discovers he has been demoted to private, charged with desertion, and assigned to a combat squad named "J" squad under the command of Master Sergeant Farell.
On the run from their enemy, the planet-destroying Gorg, the Boov find Earth a suitable place to call "home". Led by Captain Smek (Steve Martin), they commence their "friendly" invasion of the planet, relocating the humans, whom the Boov deem as simple and backwards, to other parts of the planet while the Boov inhabit their homes in a quick and bloodless conquest. One of the Boov, named Oh (Jim Parsons), is a more excited, freethinking member of the species, who decides to invite the Boov to his apartment for a housewarming party, despite the race's antipathy towards him. Not far from Oh is a preteen girl named Tip (Rihanna), who drives away through her home city to find her mother Lucy (Jennifer Lopez) after being separated from her during the invasion, leaving her with only her calico cat Pig and fueling her hatred for the Boov.
Tourists Ben Hildebrand and Eric Kirby decide to parasail around the island of Isla Sorna. A creature of unknown species attacks and kills the boat crew as it passes through a fog bank, but Ben uncouples the line, and with Eric bound with him, he goes sailing into the wilderness.
Le jeune Billy Batson se voit doter de pouvoirs par un sorcier nommé Shazam. En disant le mot « SHAZAM », dont chaque lettre lui confère les capacités et pouvoirs de plusieurs héros et figures mythologiques (la sagesse de Salomon, la force d'Hercule, l'endurance d'Atlas, la puissance de Zeus, le courage d'Achille et la vitesse de Mercure), il devient le super-héros capable de protéger Fawcett City.
As a young boy, Noah witnesses his father, Lamech, killed by a young Tubal-cain. Many years later an adult Noah is living with his wife Naameh and their sons Shem, Ham, and Japheth. After seeing a flower grow instantly from the ground and being haunted by dreams of a great flood, Noah takes them to visit his grandfather Methuselah.
In 2029, aboard the United States Air Force space station Oberon, Leo Davidson works closely with primates who are trained for space missions. His favorite simian co-worker is a chimpanzee named Pericles. With a deadly electromagnetic storm approaching the station, a small space pod piloted by Pericles is used to probe the storm. Pericles's pod heads into the storm and disappears. Against his commanding officer's orders, Leo takes a second pod and goes in pursuit of Pericles. Entering the storm, Leo loses contact with the Oberon and crashes on a planet called Ashlar in the year 5021. He discovers that the world is ruled by humanoid apes who can speak human language and treat human beings as slaves.
In April 2054, Washington, D.C. has a special police force called PreCrime that stops murderers before they act. Murders are predicted using three Precogs, mutated humans who "previsualize" crimes by receiving visions of the future. Over the past six years, PreCrime has successfully reduced the city's murder rate to zero, and the Federal government is on the verge of adopting it, even though the public finds it controversial. Captain John Anderton (Tom Cruise), the head of PreCrime, has been suffering from drug addiction since the unresolved disappearance of his son, Sean, which led to his wife, Lara (Kathryn Morris), divorcing him. With PreCrime poised to go nationwide, the system is being audited by Danny Witwer (Colin Farrell), an agent from the United States Department of Justice. In the middle of the audit, the Precogs generate a new prediction, one saying that Anderton will murder a man named Leo Crow in thirty-six hours. Anderton does not know Crow, but flees the area as Witwer begins a manhunt.
It has been four years since the events of the first movie. Seventeen-year-old Sean Anderson (Josh Hutcherson) is caught by the police after a brief chase on his dirtbike which ended with him driving into a swimming pool while trying to evade them. Minutes later, his stepfather Hank (Dwayne Johnson) arrives where a police officer (Stephen Caudill) who is friends with Hank tells him that Sean had broken into a remote satellite research center. The police officer also tells Hank that he has talked Mr. and Mrs. McGillicutty (the owners of the swimming pool) out of pressing charges. Hank takes Sean home where his mother Elizabeth (Kristin Davis) is not pleased with his actions or the fact that he and Hank don't get along well.
On July 20, 1969, astronaut Jim Lovell hosts a party, where guests watch on television as Neil Armstrong takes his first steps on the Moon during Apollo 11. After the party, Lovell, who had orbited the Moon on Apollo 8, tells his wife Marilyn that he intends to walk on the Moon's surface.
In 1944, in a German concentration camp in occupied Poland, Nazi scientist Dr. Klaus Schmidt witnesses a young Erik Lensherr bend a metal gate with his mind when the child is separated from his mother. In his office, Schmidt orders Lensherr to move a coin on his desk, and kills the boy's mother when Lensherr cannot. In grief and anger, Lensherr's magnetic power manifests, killing two guards and destroying the room. Meanwhile, at a mansion in Westchester County, New York, child telepath Charles Xavier meets young shapeshifter Raven, whose natural form is blue-skinned and scaly. Overjoyed to meet someone else "different", he invites her to live with his family as his foster sister.