Following the events of Harold & Kumar Go to White Castle, Harold Lee and Kumar Patel set off on a flight to Amsterdam so that Harold can pursue a budding romance with his neighbor, Maria. Before they board their plane, they run into a friend from college named Colton, and Kumar's ex-girlfriend, Vanessa, who are getting married in Texas. During the flight, a woman suspects Kumar is a terrorist after mistaking his bong for a bomb. Sky marshals detain the duo and the plane diverts to Washington D.C. Ron Fox, an obsessive and racist Deputy Secretary of Homeland Security, sends them to Guantanamo Bay detention camp in Cuba, thinking they are agents of a joint Al-Qaeda and North Korean conspiracy, against the advice of NSA Vice-Chairman John Beecher. With the inadvertent assistance of two other prisoners, Harold and Kumar escape and board a Cuban refugee boat to Miami, Florida. They meet up with their college friend, Raza, who loans them a car so they can travel to Texas to get help from Colton, whose family has political connections.
In 1977, Eddie Adams is a high school dropout who lives with his stepfather and emotionally abusive alcoholic mother in Torrance, California. He works at a Reseda nightclub owned by Maurice Rodriguez, where he is discovered by porn director Jack Horner, who auditions him by watching him have sex with Rollergirl, a porn starlet who always wears skates. After a heated argument with his mother about his girlfriend and sex life, Adams moves in with Horner at his San Fernando Valley home.
Cha Tae-sik leads a quiet life running a pawnshop. His only friend is a little girl, So-mi, who lives next door. So-mi's mother, Hyo-jeong, is a heroin addict who steals drugs from a feared organized crime group. She pawns her camera bag to Tae-sik; he does not realize it has the stolen drugs inside. Crime lord Oh Myung-gyu sends his subordinates, brothers Man-Seok and Jong-seok to retrieve the drugs; Jong-seok and his henchman Lum Rowan torture Hyo-jeong to find the drugs' location, then kidnap her and So-mi. Two gangsters, Du-chi and "Bear" go to Tae-sik pawn shop, but Tae-sik easily overpowers them. When he finds that Hyo-jeong and So-mi have been kidnapped, he gives them the bag, and Rowan kills Bear to set him up as the fall guy.
John Matthews (Dwayne Johnson), owner of a construction company, receives a call from his ex-wife Sylvie Collins (Melina Kanakaredes). His estranged son Jason (Rafi Gavron) is being charged with distribution of narcotics; while Jason is not actually a dealer, his friend set him up in a sting operation to reduce his own sentence after being caught. Jason's charges carry a minimum of 10 years in prison. John feels responsible because he was not there for his son, and becomes desperate as he realizes that Jason may be killed before he finishes his prison sentence.
Chev Chelios (Jason Statham) is a Chinese-based British hitman, working for a crime syndicate headed by Uglyman (Carlos Sanz). Chelios is contracted by Carlito to kill mafia boss Don Kim (Keone Young) as members of the Triads have been encroaching on Carlito's business. Carlito betrays Chelios by making it appear he assassinated Don Kim on his own, without his authorization. Ricky Verona (Jose Pablo Cantillo), an ambitious small-time criminal uses the opportunity to conspire with Carlito against Chelios; Verona will kill Chelios so the Triads do not retaliate, and then take Chelios's place as Carlito's new hired gun. While Chelios sleeps in his apartment, Verona, his brother Alex (Jay Xcala), and several henchmen break in and inject Chelios with a Chinese synthetic drug which inhibits the flow of adrenaline, slowing the heart and eventually killing the victim. Chelios wakes to find a recording left by Verona showing what he has done.
Vingt ans après avoir dérobé le butin de 16 000 £ à ses amis, Mark Renton quitte Amsterdam et retourne à Édimbourg. Il retrouve son ami Daniel "Spud" Murphy, toujours héroïnomane et en proie à des pulsions suicidaires. Il croise aussi à nouveau la route de Simon « Sick Boy » Williamson, qui vit de petites combines et tient désespérément le pub déserté de sa tante, le Port Sunshine, dans le quartier froid et pluvieux de Leith. De son côté, Francis Begbie purge une peine de 25 ans de prison. Lassé et furieux de voir ses demandes de libération refusées, il compte bien s'évader et prendre sa revanche sur Mark.
Cheech & Chong are on a mission to siphon gasoline for their next door neighbor's car, which they apparently "borrowed," and continue with their day; Cheech goes to work at a movie studio and Chong searches for something to smoke (a roach), followed by him revving up an indoor motorcycle and playing extremely loud rock music with an electric guitar that disturbs the entire neighborhood. Cheech gets fired from his job and they go to see Donna, a welfare officer and Cheech's girlfriend. Cheech successfully seduces Donna, under her objections, and gets her in trouble with her boss. The doped-up duo are expelled from the building and, in an attempt to find alternative means of income start writing songs like, "Mexican Americans" and "Beaners.
Tommy Chong plays Anthony "Man" Stoner, a jobless, marijuana-smoking drummer who is told to either get a job by sundown or be sent off to military school by his parents. Anthony leaves the house in a 1967 Volkswagen Beetle convertible (which had his father's Rolls Royce radiator grille on the front), a car which is subsequently left smoking on the side of the road. Anthony is picked up while hitchhiking by the equally enthusiastic smoker Pedro de Pacas (Cheech Marin). The license plate reads MUF DVR ("Muff Diver"). They share a large joint, which Man says is made with "mostly Maui wowie" and "Labrador" (essentially dog feces, as his dog, a Labrador Retriever, had eaten his stash). Police find their car parked on a traffic median with them in it, discover that they are clearly stoned and arrest them. At trial, the pair are released on a technicality after the judge's water pitcher is discovered to be containing vodka.
In Marseille, an undercover detective is following Alain Charnier (Fernando Rey), a wealthy French criminal who runs the largest heroin-smuggling syndicate in the world. The policeman is assassinated by Charnier's hitman, Pierre Nicoli (Marcel Bozzuffi). Charnier plans to smuggle $32 million worth of heroin into the United States by hiding it in the car of his unsuspecting friend, French television personality Henri Devereaux (Frédéric de Pasquale).
The future United States is a dystopic irradiated wasteland known as the Cursed Earth. On the east coast lies Mega-City One, a violent metropolis with 800 million residents and 17,000 crimes reported daily. The only force for order are the Judges, who act as judge, jury and executioner. Judge Dredd is tasked by the Chief Judge with evaluating new recruit Cassandra Anderson, a powerful psychic who failed the aptitude tests to be a Judge.
Actress Suzanne Vale (Meryl Streep) is a recovering drug addict trying to pick up the pieces of her acting career and get on with her life after being discharged from a rehab center to kick a cocaine-acid-Percodan habit; after overdosing while on a date, her mother admitted her to the rehab center from the emergency room. When she is ready to return to work her agent advises her the studio's insurance policy will cover her only if she lives with a "responsible" individual such as her mother Doris Mann (Shirley MacLaine) who was the reigning musical comedy star of the 1950s and '60s. Suzanne is very reluctant to return to the woman she struggled to escape from for years after growing up in her shadow. The situation is not helped by the fact that Doris is loud, competitive, manipulative, self-absorbed and given to offering her daughter unsolicited advice with insinuating value judgments while treating her like a child.
Cheech and Chong have a new business driving an ice cream truck selling "Happy Herb's Nice Dreams." However, it is not ice cream they sell, but it is marijuana, stolen from their friend Weird Jimmy whose plantation is under their beach house camouflaged as a pool. The two eventually make a fortune. They blissfully plan on becoming "Sun Kings in Paradise" which involves buying an island, guitars, and enjoying lots of women.
Three years after escaping Guantanamo Bay, best friends and roommates Harold Lee and Kumar Patel have since gone their separate ways. Harold has become a successful businessman on Wall Street, given up smoking cannabis, and married his Latina girlfriend Maria. Kumar on the other hand is poor, and still lives in the messy apartment he once shared with Harold. Kumar has recently been dumped by his girlfriend Vanessa, who arrives at Kumar's apartment to inform him that she is pregnant with his child. Maria's father and Harold's father-in-law, Mr. Perez, decides to stay at Harold and Maria's house for the Christmas holiday. Mr. Perez, who doesn't like Harold, also brings over his prized Christmas tree that he has been growing for eight years, and gives Harold a small lecture about the tree's importance. Kumar receives a package with Harold's name on it at his apartment, and decides to deliver it to Harold. At Harold's house, they discover the item inside is a large marijuana joint.
On October 6, 1970, while on holiday in Istanbul, Turkey, American college student Billy Hayes straps 2 kg of hashish blocks to his chest. While attempting to board a plane back to the United States with his girlfriend, Billy is arrested by Turkish police on high alert due to fear of terrorist attacks. He is strip-searched, photographed and questioned. After a while, a shadowy American (who is never named, but is nicknamed "Tex" by Billy due to his thick Texan accent) arrives, takes Billy to a police station and translates for Billy for one of the detectives. On questioning Billy tells them that he bought the hashish from a taxicab driver, and offers to help the police track him down in exchange for his release. Billy goes with the police to a nearby market and points out the cab driver, but when they go to arrest the cabbie, it becomes apparent that the police have no intention of keeping their end of the deal with Billy. He sees an opportunity and makes a run for it, only to get cornered and recaptured by the mysterious American.