In the prologue, which is set in medieval times, the audience is introduced to humans with special powers called The Others (Иные, иной; Inyye, Inoy). The Others are divided into two camps, with each Other either allied with the forces of Light or the forces of Darkness, and the prologue recounts a great battle between the two sides. Geser, the Lord of the Light, realized that the two forces would eventually annihilate each other. He stopped the battle and offered a truce to the forces of Darkness, led by Zavulon. To make sure each side honored its side of the agreement, the Light would have a "Night Watch" to monitor the forces of Darkness at night, and the Darkness would have a "Day Watch" to police the forces of Light during the day. This agreement maintained balance for centuries to come.
Matthew Van Helsing (Christopher Plummer), the alleged descendant of the famed 19th century Dutch medical doctor, Abraham Van Helsing, owns an antique shop in London in 2000. One night with Van Helsing upstairs, his secretary, Solina (Jennifer Esposito), allows a group of thieves (Danny Masterson, Lochlyn Munro, Sean Patrick Thomas), led by her boyfriend, Marcus (Omar Epps), into the shop. The thieves infiltrate the shop's underground high-security vault and find a sealed silver coffin protected by a deadly defense system. Based on the level of security surrounding the coffin, Solina and Marcus decide that the coffin’s contents must be valuable, so they escape with it and flee to New Orleans, Louisiana. When Van Helsing discovers that the coffin has been stolen, he boards a plane to America, telling his apprentice, Simon Sheppard (Jonny Lee Miller), to remain in London. Simon does not follow his mentor’s orders and travels to Louisiana as well.
Vampire Lestat is awakened from decades of slumber by the sound of a heavy metal band which he proceeds to take over as the lead singer. Achieving international success and planning a massive live concert, Lestat is approached by Marius, and warned that the vampires of the world will not tolerate his flamboyant public profile.
The infamous vampire Count Dracula is expelled from his castle by the Communist government of Romania, which plans to convert the structure into a training facility for gymnasts (the head trainer declares that it will include Nadia Comăneci). The world-weary Count travels to New York City with his bug-eating manservant, Renfield, and establishes himself in a hotel, but only after a mix-up at the airport causes his coffin to be accidentally sent to be the centerpiece in a funeral at a black church in Harlem. While Dracula learns that America contains such wonders as blood banks, he also proceeds to suffer the general ego-crushing that comes from modern life in the Big Apple as he romantically pursues flaky fashion model Cindy Sondheim, whom he has admired from afar and believes to be the current reincarnation of his true love (an earlier being named Mina Harker).
It is New Year's Day of 2006, more than a year after the events of Night Watch. Anton Gorodetsky, the protagonist of the first film, finds himself in the middle of an approaching conflict between the Light and Dark Others, who are still bound with an uneasy truce. Anton is still a Night Watch operative, now working with his trainee and romantic interest, Svetlana. As his son Yegor has now become a Dark Other, Anton is forced to secretly destroy evidence of Yegor's attacks on normal people, which violates the treaty, leaving the Night Watch unable to sentence Yegor.
Charley Brewster is a teenager living in a suburb of Las Vegas, Nevada, who discovers that a new neighbor has moved in next door to him. Charley's old best friend, Edward "Evil Ed" Lee, informs him that many fellow students have gone missing. When Charley goes home after school, his mother, Jane, introduces him to Jerry Dandrige, their new neighbor. Fed-up and angry with Ed after he claims that Jerry is a vampire, Charley tells him that he's crazy and that he doesn't want to be friends anymore.
Michael Emerson (Jason Patric) and his younger brother, Sam (Corey Haim), move with their recently divorced mother, Lucy (Dianne Wiest), to the beach community of Santa Carla, California. The family moves in with Lucy's father (Barnard Hughes), a cantankerous and eccentric old man who lives on the outskirts of town and enjoys taxidermy as a hobby.
Ultraviolet takes place in 2078, in the years following a global epidemic that causes vampire-like symptoms, including super-human strength and elongated canines. The infected "hemophages" die within twelve years after being infected. The "Archministry", a militant medical group headed by Vice-Cardinal Ferdinand Daxus, has taken control of the government and begun rounding up infected citizens and exterminating them in order to contain the virus.
Charles Brady and his mother Mary are Sleepwalkers—nomadic, shapeshifting energy vampires who feed off the lifeforce of virgin women. Though they normally maintain a human form, they can transform (partially or fully) into human-sized bipedal werecats (presumably their natural form) at will. They are considerably more resilient than humans and have powers of both telekinesis and illusion. Their one weakness is cats, who are not only able to see through their illusions but whose claws are capable of inflicting severe to fatal wounds upon them. It is revealed that they also maintain an incestuous relationship.
Darren Shan and his best friend Steve Leonard visit a traveling freak show. Steve believes a performer, Larten Crepsley, is a vampire. Steve talks to Crepsley after the show and asks to become a vampire. Crepsley initially refuses but is talked into testing Steve's blood, that he spits out telling Steve he has bad blood. Steve furiously swears revenge and leaves. Darren overhears everything because he has been hiding in a cupboard after stealing Crepsley's spider, Madam Octa.
Young Tony Thompson (Jonathan Lipnicki) has recently moved to Scotland, where his family takes up residence in a small castle while his father is employed building a golf course on the estate of Lord McAshton. Since arriving in his new home Tony has experienced recurring nightmares about vampires and a mysterious comet, and is bullied by his sceptical schoolmates. One night, while dressed up as a vampire, Tony is mistaken for one by the young vampire Rudolph (Rollo Weeks), who is on the run from the ruthless vampire hunter Rookery (Jim Carter). Tony helps Rudolph find a cow to feed from, and in return Rudolph takes Tony flying. The two boys quickly become friends, and Rudolph confides to Tony that his family only drink animal blood and wish to become human. When Rudolph takes Tony to the cemetery where his family lives, they are confronted by Rudolph's parents Frederick (Richard E. Grant) and Freda (Alice Krige) and Rudolph's romantic sister Anna (Anna Popplewell) and rebellious brother Gregory (Dean Cook). Frederick doubts Tony's loyalty to his son, but when Tony helps repel an attack from Rookery Frederick begrudgingly allows Tony to help them. Frederick reveals that they are searching for a magical amulet than can be used to turn vampires into humans, but Rookery is also seeking to use the amulet against them. Meanwhile, Rookery alerts Lord McAshton to the presence of vampires in the village. Lord McAshton reveals that his family has known about the existence of vampires for generations. Elizabeth, an ancestor of Lord McAshton, was romantically involved with Rudolph's uncle Von, who was the last known holder of the amulet, and both lovers were killed by the McAshtons. Learning this, Tony, Rudolph, and Anna seek out Elizabeth's tomb, where Tony experiences a vision pointing out the location of the amulet: Tony's own bedroom. Rudolph and Tony race Rookery to the amulet while the rest of Rudolph's family, along with Tony's parents, travel to the site of the ritual the vampires hope to perform. Tony and Rudolph succeed in bringing Frederick the amulet, but the ceremony is interrupted by Rookery. The vampires are unable to stand against Rookery's crosses and lights, but Tony's parents hold him off long enough for Tony to complete the ceremony by wishing for the vampires to become human. Rudolph and his family disappear as the comet passes, leaving Tony and his parents alone. Some time later, while visiting the village market, Tony spots Rudolph and his family, now human, moving into a house in the village. At first they seem not to recognize Tony, but as he calls to them their memories return, and the two friends are reunited.
The film opens with a character in a video game entering an eerie mansion. He is followed throughout the mansion by a woman in a red dress, who kills him by hanging him from a chandelier. The man playing the game is Loomis Crowley (Milo Ventimiglia), and the game is called Stay Alive. Loomis later wakes up to find his roommate and his roommate's girlfriend slaughtered. He is then hanged from a chandelier and killed, similar to the way he died in the game.
Two brothers, Seth and Richard "Richie" Gecko, having just robbed a bank, stop at a liquor store to pick up a map. When the arrival of Texas Ranger Earl McGraw threatens their getaway, they kill him and the cashier, burning down the store in the process. During the gunfight, Richie is shot in the hand. Fleeing a combined force of FBI and local police, they head towards Mexico where a contact has arranged a safe-house for them. Along the way they stop at a motel and unload a bank teller whom they are holding hostage. While Seth goes out to "sight see" checking on the border and to buy fast food burgers, Richie brutally rapes and murders the teller. Seth, who pictures himself as a professional thief, becomes furious over Richie's sadistic behavior.
Charley Brewster loves traditional Gothic horror films. He stays up late to watch the horror movie TV series Fright Night, which is hosted by his hero, Peter Vincent, a former movie vampire hunter.
In March 1983, in Los Alamos, New Mexico, a disfigured man is taken to the hospital. An unnamed police detective (Elias Koteas) tries to question him about a recent murder. The detective is called to a phone and told that the man's daughter was just downstairs. While he is on the phone, the man jumps out of the window, leaving behind a scrawled note that reads "I'm sorry Abby."