After a nuclear war, the people of the planet Davanna developed an incurable blood disease. One of its citizens is sent to Earth to examine the blood of the humans for its usefulness in curing Davanna's dying race. The intruder (Paul Birch) has adopted the name Mr. Johnson, conspicuous only for his oversensitive ears and his sunglasses, which he wears even in the dark. The sunglasses hide his blank, white-eyed stare which kills his victims by burning through their eyes and into their brains.
After a dying Voodoo queen, Mama Loa, chooses an adopted apprentice, Lisa Fortier (Pam Grier) as her successor, her arrogant son and true heir, Willis, (Richard Lawson) is outraged. Seeking revenge, he buys the bones of Mamuwalde the vampire from the former shaman of the voodoo cult, and uses voodoo to resurrect the vampire to do his bidding. However, while it brings Mamuwalde back to life, he quickly bites Willis upon awakening. Willis now finds himself in a curse of his own doing: made into a vampire hungering for blood and, ironically, a slave to the very creature he sought to control. Meanwhile, Justin Carter (Don Mitchell), an ex-police officer with a large collection of acquired African antiquities and an interest in the occult, begins to investigate the murders caused by Mamuwalde and his growing vampire horde. Justin meets Mamuwalde at a party Justin hosts to display the African collection pieces before being moved to the University's museum. They discuss the artifacts, unbeknown to anyone else, that were from the region of Africa Mamuwalde hails from, including pieces of jewelry once worn by his late wife Luva. Mamuwalde also meets Justin's girlfriend, Lisa Fortier, at the party and he discovers that Lisa is naturally adept at voodoo. Lisa discovers Mamuwaldes' true nature after a friend of hers, Gloria, falls victim to his bite and resurrected as a vampire who nearly feeds on her if not for Mamuwalde's intervention. He later asks her for help to cure him of his vampire curse. Justin, with the help of L.A.P.D. Lieutenant Harley Dunlop (Michael Conrad), pulls together several other cops to go to the Mamuwalde residence to investigate the recent deaths. While Lisa is performing the ritual to cure Mamuwalde, using a voodoo doll fashioned to look like him, Justin, Harley and their men raid the house, fighting against Blacula's vampire minions which include several friends of theirs. Willis is killed during this scuffle. Justin manages to find Lisa and Mamuwalde and interrupts the ritual. Lisa refuses to help Mamuwalde after she witnesses him kill the other police officers in the house in a fit of rage. As Mamuwalde, now calling himself Blacula, is about to bite Justin, Lisa stabs the prince's voodoo doll killing Mamuwalde and destroying the menace of Blacula forever.
The setting of the film is 1920s London. Sir Roger Balfour is found shot to death in his home. Inspector Burke (Lon Chaney) of Scotland Yard is called in to investigate. The suspects are Williams (the butler), Sir James Hamlin (Henry B. Walthall) and his nephew, Arthur Hibbs (Conrad Nagel). A suicide note is found and the case is supposedly closed.
In a small suburban town, a group of university students--Mark Loftmore (Zach Galligan), China Webster (Michelle Johnson), Sarah Brightman (Deborah Foreman), Gemma (Clare Carey), James (Eric Brown) and Tony (Dana Ashbrook)--visit a mysterious wax museum, where they encounter several morbid displays, all of which contain stock characters from the horror genre. Tony and China unintentionally enter two separate pocket worlds, as depicted by the waxwork displays, by crossing the exhibition barrier rope. Tony is at a cabin where a werewolf (John Rhys-Davies) attacks him. A hunter and his son arrive and try to kill the werewolf. The son fails and is torn in two, while the hunter shoots the werewolf, and then shoots Tony as he begins to transform into a werewolf. China is sent to a Gothic castle, where vampires attack her and Count Dracula (Miles O'Keeffe) turns her into a vampire. Two of the other students, Mark and Sarah, leave the waxwork unscathed. Later, Jonathan (Micah Grant), "a college jock", arrives at the wax museum, looking for China, but The Phantom of the Opera display gets his attention as David Lincoln (David Warner) walks him into the display. Mark goes to a pair of investigating police detectives, Inspector Roberts (Charles McCaughan), and meets Lincoln as he lets Roberts investigate the waxworks. As Mark and Roberts leave the Museum, Mark recognizes Lincoln.
The film starts with Bold Cheung having a nightmare about ghosts.
Bold Cheung is challenged to spend the night in an abandoned house where he must peel an apple in front of a mirror. If he breaks the skin then something bad will happen. Upholding his mantle as the boldest he accepts. However, that night whilst peeling the apple his friends trick him. Whilst scolding his friend for the prank a real ghost appears and snatches Cheung's friend away. The ghost reaches for Cheung but he cuts its hand off and then quickly shattering the mirror, causing the house to collapse.
Peter Loew (Nicolas Cage) is a driven literary agent, who is slowly going insane. He works all day, and club hops at night, with little in his life but one night stands and the pursuit of money and prestige. He sees a therapist (Ashley) frequently, and during these sessions, his declining mental health becomes clear through a series of increasingly bizarre rants that eventually begin to scare even his psychiatrist. After taking a girl he met in a club named Jackie (Kasi Lemmons) back to his place, a bat flies in through his window, scaring them both.
Renfield is a solicitor traveling to Count Dracula's castle in Transylvania on a business matter. The people in the local village fear that vampires inhabit the castle and warn Renfield not to go there. Renfield refuses to stay at the inn and asks his carriage driver to take him to the Borgo Pass. Renfield is driven to the castle by Dracula's coach, with Dracula disguised as the driver. En route, Renfield sticks his head out the window to ask the driver to slow down, but sees the driver has disappeared; a bat leads the horses.
In the year 1536, an alchemist in Veracruz developed a mechanism that could give eternal life. In 1937, an old building collapsed and the alchemist with marble white skin is killed when his heart is pierced by the debris. Investigators never revealed what else was discovered in the building: basins filled with blood from a corpse.
A Secret Service agent (Maurice O'Connell) barely escapes from an English country house, in which satanic rituals are celebrated. Before he dies of his wounds, he reveals to his superiors that four prominent members of society – a government minister, a peer, a general and a famous scientist – are involved in the cult, led by Chin Yang (Barbara Yu Ling). Photos of the four dignitaries taken by the agent are developed, and a fifth photo, apparently showing an empty doorway, is assumed to be a mistake. In order to avoid any reprisals by the minister, secret service official Colonel Mathews (Richard Vernon) calls in Scotland Yard's Inspector Murray (Michael Coles) to work on the case independently. Murray (who had appeared in the preceding Dracula film) suggests consulting noted occult expert Professor Lorrimar Van Helsing (Peter Cushing).
In Mexico, a freelance vampire slayer, Derek Bliss (Jon Bon Jovi), is hired by an unknown client provided he build a team of slayers. Father Adam Guiteau (played by Tim Guinee in the first film) is shown to have been killed in this one. This team ends up including the vampiress Zoe, who is fighting her affliction with medication, Father Rodrigo, a helper who pretends to be a priest, and Sancho, a brave fourteen-year-old boy who aids Derek in killing some vampires at the beginning of the movie, in finding a large nest of "suckers" and their powerful leader, a vampire princess named Una (Arly Jover). She is seeking a legendary black crucifix: the Berziers Cross, the same crucifix used unsuccessfully in the first movie to perform a ritual which will enable vampires to walk in sunlight and be invulnerable.
A young, hardworking Iranian man named Arash lives with and takes care of his heroin addicted father, Hossein. They are harassed by a cruel, drug-dealer pimp named Saeed, who seizes the young man’s prized car in exchange for money the father owes him. In a crime of opportunity, Arash steals a pair of diamond earrings from the wealthy young woman he works for. The pimp comes across a strange, young woman in a chador at night, and back at his apartment she grows long fangs and goes for his neck. As she leaves she passes by the young man, who has come to offer the earrings for his car. He finds the drug dealer dead, taking back his car keys, along with the drugs and cash. The young man dresses up as Dracula, and goes to a night club where he is seduced into taking one of the “X” pills he is selling by a young woman he knows. Under the influence, he is rejected by her, and ends up lost at night on the street.
A prologue replays the final scenes from Dracula, in which Dr. Van Helsing (Peter Cushing) destroys Dracula (Christopher Lee) by driving him into the sunlight. These scenes are accompanied by voice-over narration that describes how Van Helsing, a scholar of vampirism, was able to end Dracula's century-long reign of terror and destroy his cult; only the memory of Dracula's evil remains.
Kathleen Conklin (Taylor), a young philosophy student at New York University, is attacked by a woman (Annabella Sciorra), who tells her "order me to go away" and, when the frightened Kathleen is unable to do so, bites her neck and drinks her blood. Kathleen develops several of the traditional symptoms of vampirism, including aversion to daylight, but the film's main focus is on her moral degradation. It is hinted that vampires become immortal in this film, but the price is an addiction to blood. Vampires are shown repeatedly resorting to the strategy of blaming their victims for not being strong enough to resist them. As one of Kathleen's victims weeps incredulously over the damage, Kathleen coldly informs her: "My indifference is not the concern here - it's your astonishment that needs studying." Eventually Kathleen meets Peina (Walken), who claims to have almost conquered his addiction, and as a result is almost human. For a time he keeps her in his home trying to help her overcome hers, recommending that she read William S. Burroughs' Naked Lunch. At her graduation party, she says "I'd like to share a little bit of what I've learned" she and her victims (now vampires themselves) attack the party goers, participating in a bloody, chaotic vampire orgy.
Beckett (Sophie Curtis) is a beautiful young teenager that is still mourning the loss of her mother. She's moved to the Upper West Side of Manhattan with her father Miles (Linus Roache) and is set to begin school at Hamilton, an exclusive prep school. Beckett is so engrossed in her grief that she fails to notice that her school is a little stranger than most schools, as its students are prone to suicides and is full of extraordinarily beautiful female teachers. Things grow worse when the school nurse Pamela (Kelly Reilly) decides to move in with Beckett and Miles, especially since Pamela keeps instructing Beckett to remain a virgin. What Beckett doesn't know is that Pamela and the other school staff are all incarnations of Lamia, a former queen of Libya, and must kill and drink the blood of virgins to retain their immortal existence.
Mr. Kau is a Taoist priest who performs magic that maintains control over spirits and irrepressible vampires. Together with his inept students, Man Choi and Chau-Sang, he resides in a large house protected from the spiritual world with talismans and amulets.