In rural Indiana, Noah Daly (Jordon Hodges) and his impoverished family wrestle with the mysterious return of his now mute sister Lauren (Anne Winters), who was kidnapped and held captive for over a decade.
The film centers around six children that have been sent to a strange, mysterious house by their wealthy parents, who feel that their children pose more of a burden than a blessing. While in the house they will face seven monsters, each of which are intent on battling the children.
Ed Cole (Haley Joel Osment) feels like he is letting his life go by without him. He leaves his job at a bagel shop and works as an after-school detention teacher after impressing the principal (Matt Walsh). He moves out of his apartment, allowing his roommate JT (Glen Powell) to engage in kinky sex with his girlfriend Ally (Castille Landon). While working with his students, Ed realizes most of the troubled youths are sexually confused, and begins an after school sex ed program. At the same time JT convinces Ed to have sex with someone to end his dry spell, leading to a disastrous blind date with Trish (Abby Elliott), a former co-ed.
Four elderly patients at a nursing home have made friends and play cards most days when they are feeling up to it. Unfortunately Frank is slowing down and is on a lot of medication such as insulin and suffers from strokes. June has dementia and is sometimes barely able to recognise who she is talking to or holding a conversation that's inline with what is being discussed. Ella is upset from breaking her hip from merely sitting in a chair due to her old age. Alice is still bubbly and hanging on her hopes of winning the lottery.